https://www.organscigroup.us/journals/open-journal-of-asthma A Peertechz Open Access Journal en-us 08 Jul, 2025 https://www.organscigroup.us/articles/OJA-9-121.php Background: Childhood asthma keeps rising, and what lands on the dinner table may stoke or soothe young airways. Understanding the dietary influences shaping this epidemic is both a public health priority and a culinary question. Objective: This scoping review charts the past decade of research exploring how whole diets, individual nutrients, and body weight affect asthma in children while highlighting culturally grounded dietary interventions. Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Scoping Review guidance. Searches of eight databases and gray literature captured observational and experimental studies published from January 2015 to May 2025 on diet and asthma in individuals from birth to eighteen years. Two reviewers screened, extracted, and assessed quality. Results: Plant-rich patterns, including Mediterranean and Dietary Approaches to Stop Hypertension (DASH) menus, were associated with fifteen to fifty percent fewer wheezing episodes, while fast food, sugar-sweetened drinks, and other ultra-processed foods coincided with more attacks and hospital visits. Six trials that boosted fruits, vegetables, fish, or weight loss improved symptoms within six months; high-dose vitamin D and other single-nutrient pills rarely helped. Conclusion: Diet quality and body weight are modifiable determinants of paediatric asthma worldwide. Clinicians should incorporate nutrition and weight counselling into asthma management, and public health policies that promote affordable, minimally processed foods may lessen disease burden. Future multicentre trials should test comprehensive dietary interventions and clarify microbiome-mediated mechanisms. Standardised outcome sets will enhance comparability across future nutritional trials worldwide and registries. 29 Oct, 2022 https://www.organscigroup.us/articles/OJA-6-118.php At the end of 2019, in Wuhan, China, an outbreak of cases of respiratory tract infection emerged and its progressive infection mainly affects adults, generating many cases of pneumonia. A type of coronavirus named SARS-CoV-2, with genomic similarity to SARS-CoV and MERS-CoV, was identified as the etiological agent. The evolution of this pandemic has made it possible to verify the similarity in the pathophysiological mechanisms between these three viruses, identifying the Angiotensin-Converting protein-Enzyme 2 (ACE2) as the primary receptor for SARS-CoV-2. This age group is more prone to developing extrapulmonary complications from SARS-CoV-2 since the clinical and pathological findings suggest a particular relationship between greater expression of ACE2 and the comorbidities of chronic degenerative diseases and the greater expression of ACE2 at the level of the respiratory tract. It has also revealed the mechanisms by which the virus evades the innate immune response and the Th1-type adaptive response. The objective of this work was to analyze immunosenescence and its relationship with SARS-CoV-2 infection, through the review of the most recent articles (2021-2022), which describes the senescent state of the elderly. In addition, it intends to highlight the probable causes for which the most vulnerable population group (adults over 60 years of age) is more prone to presenting complications during the infection. 28 Sep, 2022 https://www.organscigroup.us/articles/OJA-6-117.php Background: Although asthma is a common disease accurate diagnosis is missing and it has been reported that often it is over or under-diagnosed. Aim: To investigate if a physician’s diagnosis of asthma in Cyprus is correct by using a structured algorithm at the outpatient primary care level. Subjects and Methods: Sixty adults with a self-reported physician diagnosis of asthma, mean age of 47,8 years (29 males and 31 females) were included in the study. Medical history and physical examination, pre-post bronchodilation spirometry and methacholine bronchial challenge test was used to confirm or rule out the diagnosis as well as a three months follow-up. In addition, the cost of treatment was estimated. Results: Sixteen subjects (27%) had a positive pre-post bronchodilation spirometric test and were considered asthmatics. In 9 out of the 44 remaining subjects a positive Methacholine provocation test confirmed the diagnosis of asthma. The rest of the subjects (n = 35) went into a 3 months observational period during which only 2 showed asthmatic symptoms and were considered asthmatics by a second methacholine test that confirmed the diagnosis. Therefore, a correct asthma diagnosis was established in only 27(45%) of subjects. The annual average cost of medication for asthma confirmed the group was 313 euro/patient (171-454, 95% CI) and the average 2-year unnecessary (asthma ruled-out group) cost of treatment was approximately 297 euro/patient. (179-415, 95% CI). Conclusions: Physician-diagnosed asthma overestimates the actual prevalence of disease in adults in Cyprus since it was shown that more than half of the participants did not have Asthma. These individuals consume unneeded medications at a significant cost. Thus, the correct diagnosis of Asthma should be made by using more specific tests starting at the primary care level. 24 Aug, 2021 https://www.organscigroup.us/articles/OJA-5-116.php Asthma is a complicated chronic airway disease that characterized by structural and functional changes responsible for airway hyperresponsiveness and usually reversible airway obstruction. Allergic asthma is widely triggered by an immune-inflammatory response driven by Th2 lymphocytes and these cells contribute to the pathogenesis of asthma, thus worsening its severity. Airway hyperresponsiveness, 30 Jul, 2021 https://www.organscigroup.us/articles/OJA-5-115.php Through stern social restraint measures, Italy has recently overcome the epidemic peak of COVID-19 (Coronavirus Disease-19) respiratory syndrome induced by SARS-CoV-2 and the attention is progressively moving toward its sequelae, especially on pulmonary fibrosis and the associated pulmonary functional decline [1-3]. 15 Jul, 2021 https://www.organscigroup.us/articles/OJA-5-114.php The COVID pandemic brought healthcare systems close to the breaking point and stimulated research which has led to an effective vaccine, but no reliably effective antiviral medication to treat active infection. A prioritization of transmission risk reduction has emphasized patient isolation and PPE for healthcare workers and others. Clinical management improved somewhat with inclusion of corticosteroid but remained primarily supportive in nature. Mucus mobilization has not been perceived as a priority for preventing or treating disease. Furthermore, proning ventilated patients is practiced intermittently and is not prioritized in managing ventilated patients, as it is rarely recommended. Mucociliary clearance (MCC) forms the backdrop for a mucocentric perspective on COVID and other respiratory conditions. Objective measures of MCC and mucus burden are lacking, but it is likely these factors that play a significant role in infection risk and variability of clinical course. The identified high-risk groups share a feature of impaired awareness and response to the presence of excess mucus. While further research is needed, safe and cost-effective steps based on improving MCC are available for immediate implementation: these include strategic body positioning, upper respiratory care, refinement of cough technique and airway hydration. 19 Aug, 2020 https://www.organscigroup.us/articles/OJA-4-113.php Asthma is a chronic airway disease with two characteristic features: (1) chronic airway inflammation (the most common eosinophilic airway inflammation) and (2) airway hyperresponsiveness (excessive airway constriction by normal triggers) [1]. Management of asthma requires long-term treatment to achieve well-controlled symptoms and prevent the risk of exacerbation in future. Inhaled corticosteroid (ICS) is the mainstay therapy of asthma with strong evidences [2]. Nonetheless it is still the existence of gap in knowledge “what is the most appropriate dose of ICS to treat asthmatic patient?”. 24 Jun, 2020 https://www.organscigroup.us/articles/OJA-4-112.php In this season where lung related ailments are more manifest, controlling asthma should be seen as a major win in respiratory health considering its devastating effect. 15 Jun, 2020 https://www.organscigroup.us/articles/OJA-4-111.php A large body of studies showed emotional, psychopathological and personality correlates of asthma but failed to identify a specific psychological type and specific sources of stress for asthma. The purpose was to identify psychological correlates specific to asthma that would unravel characteristic sources of stress. The study was done in the framework of the cognitive orientation theory which assumes that cognitive contents and processes affect physiological processes. The subjects were 34 asthma patients (7 yrs mean duration) and 43 matched controls (mean age 22-23 yrs). All subjects were administered a questionnaire assessing beliefs of 4 types (goals, norms, self and general) referring to 19 themes identified in pretests as relevant. The results showed that there is a set of beliefs characterizing asthma patients in terms of all belief types and themes (e.g., obsessive-compulsive, ambition, perfection) that enabled identifying asthma patients significantly by means of a stepwise discriminant analysis. The findings show that there is a characteristic asthma type and specific sources of stress dependent on stress-generating themes (e.g., not expressing anger, fear of rejection) and conflicts (i.e., striving for closeness to others vs withdrawal from others, behaving in conformity with commitments vs rejecting all in favor of personal freedom, and a discrepancy between view of self and of others). 09 Dec, 2019 https://www.organscigroup.us/articles/OJA-3-110.php Introduction: Smoking in asthma patients is an important factor contributing to worsened control of asthma. Despite increased awareness of the harmful effects of smoking in patients with asthma, a significant proportion of asthmatics remain smokers. Here, we present findings from the Still Fighting for Breath global survey regarding the prevalence of smoking in patients with severe asthma, impact of smoking on asthma control and correlation of smoking with different aspects of quality of life in patients with severe persistent asthma. 06 Nov, 2018 https://www.organscigroup.us/articles/OJA-2-109.php Background: Many studies showed a low risk of asthma in sub-Saharan countries. However, due to indoor pollutions and environmental hazards, developing countries are always the prior victims of all types of respiratory illnesses including asthma. Jimma, south-western Ethiopia, is known by its wide range of vegetations including khat and coffee. Together with high plantation of those cash crops, there is widespread consumption of them by the locals. 18 May, 2018 https://www.organscigroup.us/articles/OJA-2-108.php Introduction: Asthma is a chronic inflammatory disorder of the airways. It is always being a health burden across the globe. The active chemical present in Khat could have a bronchodilator effect like that of catecholamine. 11 May, 2018 https://www.organscigroup.us/articles/OJA-2-107.php Introduction: Asthma is a common chronic inflammatory disorder affecting about 300 million people worldwide. As a holistic therapy, yoga has the potential to relieve both the physical and psychological suffering of people with asthma, and its popularity has expanded globally. Yoga includes several techniques: physical postures (asanas), voluntarily regulated breathing (pranayama) and meditation. 27 Jun, 2017 https://www.organscigroup.us/articles/OJA-1-106.php Introduction: Aerosol therapy consists of spraying liquid particles suspended for therapeutic purposes in the respiratory tract. With direct absorption and deposition at the lung level, avoiding side effects and presenting fast response time. 25 May, 2017 https://www.organscigroup.us/articles/OJA-1-105.php No one really knows what exactly caused asthma. However, recent studies revealed that exposure to magnetic fields increases asthma risk and make asthma victims worst. This case study was aimed at determining the extent of the symptoms of asthma among victims when they stayed within and were moved away from the geopathic zone. 12 Apr, 2017 https://www.organscigroup.us/articles/OJA-1-104.php Background: Asthma among obese represents a unique phenotype. Mast cells are more abundant in obese. Serum tryptase (ST) is a marker of mast cell numbers or activity. Since obesity and asthma have been linked in epidemiological studies, a possible higher mast cell activity in obesity could be a factor between the two conditions. This study was to investigate ST and its potential association between obesity and childhood asthma. 04 Mar, 2017 https://www.organscigroup.us/articles/OJA-1-103.php Background: Several studies have linked dietary intake and asthma symptoms, nevertheless the results are still inconclusive and data from developing country are scarce. Objective: To assess the association of Food patterns and current asthma symptoms in school-aged children from rural and urban areas of Oropeza Province – Bolivia. 10 Feb, 2017 https://www.organscigroup.us/articles/OJA-1-102.php Background: To determine whether a child has asthma exacerbation, we should obtain the value of peak expiratory fl ow. It is useful in a diagnostic procedure, in evaluation of response to therapy and following the course of asthma. 03 Jan, 2017 https://www.organscigroup.us/articles/OJA-1-101.php This review paper covered stress, management related to asthma, trauma, sepsis, inflammation along with anxiety, and depression that occurs both in women with asthma, traumatic children and adult patients.