ISSN: 2640-8139
Annals of Musculoskeletal Medicine
Research Article       Open access      Peer-Reviewed

Weight Loss Programs fail in obese children with Blount’s and SCFE

Gregory I Pace, William L Hennrikus*

Department of Orthopaedics, Penn State College of Medicine, USA
*Corresponding author: William L Hennrikus, Department of Orthopaedics, Penn State College of Medicine, USA, Tel: 717-531-7006; Fax: 717-531-0216, E-mail:
Received: 05 June, 2017 | Accepted: 26 June, 2017 | Published: 27 June, 2017
Keywords: Childhood obesity; Blount’s Disease; SCFE; Weight loss

Cite this as

Pace GI, Hennrikus WL (2017) Weight Loss Programs fail in obese children with Blount’s and SCFE. Ann Musculoskelet Med 1(1): 022-027. DOI: 10.17352/amm.000005

Introduction: Slipped capital femoral epiphysis (SCFE) and Blount’s disease in children are associated with obesity. The purpose of this study is to evaluate the effectiveness of pediatric weight management programs in achieving weight loss in overweight children with SCFE and Blount’s disease.

Methods: A retrospective review of medical records was performed on children treated surgically for SCFE and Blount’s Disease between 2008 and 2013 by the senior author (WH). All patients in the study were overweight or obese.

Results: Sixteen females and 17 males with a mean age of 12.7 years were identified. All patients were offered a referral for weight loss management. 17 (52%) patients accepted the offer for a weight loss consultation and 12 (36%) actually attended the pediatric weight loss center. Patients who attended the pediatric weight loss center experienced a larger increase in BMI during follow-up compared to patients who did not attend the weight loss center.

Conclusions: Adolescents with SCFE or Blount’s disease showed poor compliance in attending a weight management center. Furthermore, patients who attended the weight loss clinic failed to decrease their BMI.


The association between obesity and Slipped Capital Femoral Epiphysis (SCFE) and Blount’s disease in children is well established in the literature [1-3]. Approximately two-thirds of patients with Blount’s disease are obese and up to 80% of patients with SCFE are overweight or obese [1,4]. Increased stress placed on the tibia and femur of overweight and obese children predisposes them to the development of deformity. In these patients, excess weight overcomes the tensile strength of bone and cartilage leading to undergrowth of the medial aspect of the proximal tibial metaphysis in Blount’s disease. Similarly, excess weight places increased stress on the cartilaginous growth plate of the hip leading to SCFE [4,5]. Obese children are also prone to develop additional musculoskeletal conditions, including flat feet, fractures, fracture complications, and complications following spinal surgery for scoliosis [6-13].

Recent studies have shown that obese children with Blount’s and SCFE are at risk for disease progression [1-3,14]. Nasreddine and Kocher et al., suggested that a supervised weight loss program for patients being managed for unilateral SCFE may minimize progression to bilateral involvement [15]. Stimulated by Nasreddine’s conclusions, we designed a study to examine the effectiveness of a supervised weight loss program for patients with SCFE and Blount’s disease. The aim of this study was to evaluate the effectiveness of a pediatric weight management program in achieving weight loss in overweight and obese children with SCFE and Blount’s disease.


This study was approved by the hospital’s Institutional Review Board. The senior author’s database was used to identify patients with a diagnosis of Blount’s disease or SCFE who had undergone surgery related to this diagnosis between 2008 and 2013. Patients were excluded if they were older than 18 years of age at the time of their initial surgery or if they were of normal weight. The medical records of identified patients were reviewed retrospectively and demographic and clinical information was collected for each patient (Table 1).

The CDC BMI Percentile Calculator for Child and Teen was used to calculate child BMI percentile-for-age scores. Patients with a BMI percentile-for-age less than the 85th percentile were considered of healthy weight, between the 85th and 95th percentile-for-age were overweight, greater than the 95th percentile-for-age were considered obese, and patients with a BMI greater than the 99Th percentile-for-age were considered severely obese [16,17].

The weight loss methods utilized by our hospital’s pediatric weight loss center entailed a multidisciplinary approach centered on diet modification and exercise. The children were treated by registered dieticians, exercise physiologists, and pediatricians with expertise in obesity management. Each patient underwent a comprehensive medical evaluation and was provided with an individualized meal plan that centered on decreasing meal portion size and sugary drink consumption. A balanced and nutritious diet was designed for each patient participating in the program. Additionally, each patient had a consult with an exercise physiologist to increase their physical activity while decreasing lifestyle activities that promote a sedentary lifestyle. The exercise program included at least 60 minutes of physical activity daily, aerobic exercises, and limiting television and computer use to less than two hours daily. All patients had an initial assessment and were followed up on a quarterly basis. Psychological assessments of the patients, and assessment of parenting skills, were not performed routinely. No patient had a medical problem prohibiting them from attending the weight loss clinic. Due to the outpatient nature of the obesity management program, compliance with the recommendations of the weight loss clinic could not be accurately measured.

The mean values of each patient’s BMI preoperatively and at latest follow-up were compared using the paired t-test. The effect of variables such as sex, ethnicity, laterality, progression to bilateral SCFE, and weight loss clinic attendance on the change in BMI between the preoperative visit and most recent follow-up was compared using the unpaired t-test. Statistical significance was defined as p<0.05.


During the study period, 43 patients aged 18 or younger underwent surgical treatment for either SCFE or Blount’s disease. Four patients were excluded for inadequate medical records and six patients were excluded because they had a BMI <85th percentile-for-age. Therefore, the final analysis consisted of 33 patients--16 females and 17 males-- with an average age of 12.7 years (range, 3.6 to 18.0 years). Nineteen (58%) patients had a family history of diabetes. We did not collect data on the weight of the parents or any family members. Subject demographic details are noted (Table 1).

Patient details regarding BMI, weight, and BMI percentile-for-age at the initial visit and most recent follow-up were assessed (Table 2). Patient average initial weight was 80.4 kg (range, 42.5-144.1 kg) and final weight was 95.4 kg (range, 43.8-153.7 kg). Preoperatively, 6 (18%) patients were overweight, 13 (39%) were obese, and 14 (43%) were severely obese. At an average follow-up of 24 months, the mean patient BMI increased from 32.4 kg/cm2 to 34.8 kg/cm2 (p=0.001). Compared with their preoperative BMI, 25 (76%) children had an increase in their BMI at the latest follow-up. Only one subject who presented with unilateral SCFE progressed to bilateral SCFE during the course of the study.

All thirty-three patients were offered a referral for weight loss management at the first or second postoperative visit. Twelve (36%) patients attended the pediatric weight loss center. Patients who attended the weight loss clinic had an initial BMI of 36.9 kg/cm2 and a last follow-up BMI of 40.3 kg/cm2 (p=0.003). The remaining 21 patients who did not attend a weight loss clinic had an initial BMI of 29.7 kg/cm2 and a last follow-up BMI of 31.7 kg/cm2 (p=0.06). Therefore, patients who attended the weight loss center experienced an average increase in BMI of 3.4 kg/cm2, a 10% increase, compared to an average increase of 2.0 kg/cm2 (p=0.35), a 7% increase, for those patients who did not attend the weight loss clinic.

Factors assessed for a possible relationship as to whether or not patients attended the weight loss clinic included patient gender, race, diagnosis and BMI (Table 3). Only patient BMI at the initial visit was significant. Patients accepting a referral for weight loss management had an average initial BMI of 36.7 kg/cm2 compared to 27.8 kg/cm2 (p=0.001) for patients refusing a referral. Similarly, patients who attended the weight loss clinic had an average initial BMI of 36.9 kg/cm2 compared to 29.7 kg/cm2 (p=0.01) for patients who did not. Other factors examined including patient gender, race, and diagnosis were not significant (Table 3).


Childhood obesity is a global public heath epidemic predisposing children to the development of significant medical morbidities involving nearly every organ-system, including several musculoskeletal conditions [6-13,18]. The direct costs of childhood obesity in the U.S. alone exceed $14 billion dollars annually [19]. Additionally, studies have shown that approximately one-third school-age children in the U.S. are overweight or obese, and about half these children will become obese adults with the estimated annual cost of treating obesity-related illness in adults approaching an additional $147 billion [20]. The link between obesity and the SCFE and Blount’s disease has been previously published [1-3,6,21]. Our study similarly shows a strong association of SCFE and Blount’s disease with an elevated BMI as 81% (35/43) of patients were overweight or obese, and 37% (16/43) of patients were severely obese-- (BMI percentile-for-age greater than the 99th percentile)-- at the time of the initial visit.

Our results indicate that the pediatric weight loss program at our institution is ineffective in achieving weight loss in overweight and obese children with SCFE and Blount’s disease. This failure is either due to the program being ineffective or the recommendation not being respected. However, due to the outpatient nature of the program compliance with the recommendations of the weight loss program could not be accurately measured. Despite attending a multidisciplinary clinic that included the expertise of physicians, dieticians, and exercise physiologists, children attending the weight loss management program not only failed to decrease their BMI, but instead showed an overall increase in BMI during the follow-up period. In fact, only two patients (16%) who attended the weight loss clinic had a decrease in BMI at final follow-up. The failure to lose weight was not unique to this particular clinics program [22,23].

Weight loss clinics in general are unsuccessful for most children. Several studies have similarly reported limited effectiveness of interventions aimed at achieving weight loss in overweight children [24-27]. For example, a recent study by Reinehr et al., of 11,681 overweight children treated at 175 centers specialized in pediatric obesity care in Central Europe found a mean reduction of only -0.15 SDS-BMI over a period of 1.2 years. Reinehr therefore concluded that these centers fail to achieve clinically relevant weight loss in overweight pediatric patients [28]. A few trials have demonstrated efficacy of lifestyle interventions in overweight children under ideal circumstances [26,27,29], however, when studied under real-life conditions pediatric weight loss centers report poor results [24-26]. Studies showing poor results cite a lack of psychosocial support and parenting skills, poor motivation for lifestyle changes, and constraints to therapy compliance [26]. In our study only 71% of patients who accepted a weight loss evaluation actually attended the weight loss clinic, however we were not able to measure each patient’s compliance with the weight loss recommendations among patients who attended the weight loss program. In addition, 48% of patients refused the initial offer for a weight loss evaluation, reflecting significant misperception by the parent and child that the patient’s obesity was a significant health issue. A recent publication by Duncan et al. found that as high as 78% of parents perceived their obese child as just about the right weight, revealing a significant misperception of children’s body weight by parent’s [30]. According to our results, however, there appears to be a point at which patients or their parents are unable to deny their weight status, as the BMI of patients who accepted a referral and attended a weight loss program was significantly higher compared to those who did not.

Lifestyle modification through caloric restriction and enhanced exercise and physical activity remain key treatments for obesity in most children. Medications such as Orlistat and Sibutramine have been utilized but challenged due to serious adverse side effects such as gastrointestinal, cardiac, and neurological complications [22,31]. In the current study, no weight loss medication treatments were used.

Future avenues of research in pediatric weight loss include bariatric surgery. Bariatric surgery for adolescents as a treatment for obesity has risen steadily over the last several years; however many pediatricians are often reluctant to refer patients for surgery due to the perceived risk [33-35]. Reported complication rates for gastric bypass surgery are low and clinically significant BMI reductions have been shown [33,36-38].

Limitations of this study include its retrospective nature, small sample size, and potential selection bias of patients who attended the weight loss program. In addition, we were not able to measure patient compliance with the recommendations prescribed by professionals at the weight loss center. Furthermore, due to our lack of long-term follow up we don’t know the long-term orthopaedic consequences of these patients not losing weight. Other factors can influence the development of obesity in adolescents including the psychiatric state of the patients, alterations in eating habits, and psychosocial components, and these were not studied in this paper. The results of this preliminary study would be supported by a prospective study with comparison groups in the future.


The current study demonstrates a near complete failure of one centers comprehensive pediatric weight loss clinic to reduce weight in obese children with SCFE and Blount’s disease. Eighty-three percent of patients who attended the weight loss clinic demonstrated an increase in BMI at 2 years follow up. Without a comprehensive cultural change in the food industry and a behavioral change among children we foresee very little success in weight loss programs for obese children with SCFE and Blount’s disease.

  1. Manoff EM, Banffy MB, Winell JJ (2005) Relationship between Body Mass Index and slipped capital femoral epiphysis. J Pediatr Orthop 25: 744-746. Link:
  2. Bhatia NN, Pirpiris M, Otsuka NY (2006) Body mass index in patients with slipped capital femoral epiphysis. J Pediatr Orthop 26: 197-199. Link:
  3. Scott AC, Kelly CH, Sullivan E (2007) Body mass index as a prognostic factor in development of infantile Blount disease. J Pediatr Orthop 27: 921-925. Link:
  4. Dietz WH (1998) Health consequences of obesity in youth: childhood predictors of adult disease. Pediatrics. 101: 518-525. Link:
  5. Cook SD, Lavernia CJ, Burke SW, Skinner HB, Haddad RJ (1983) A biomechanical analysis of the etiology of tibia vara. J Pediatr Orthop 3: 449-454. Link:
  6. Wills M (2004) Orthopedic complications of childhood obesity. Pediatr Phys Ther 16: 230-235. Link:
  7. Seeley MA, Gagnier JJ, Srinivasan RC, Hensinger RN, VanderHave KL, et al. (2014) Obesity and its effects on pediatric supracondylar humeral fractures. J Bone Joint Surg Am 96: e18. Link:
  8. Gettys FK, Jackson JB, Frick SL (2011) Obesity in pediatric orthopaedics. Orthop Clin North Am 42: 95-105. Link:
  9. Sabharwal S (2009) Blount disease. J Bone Joint Surg Am 91: 1758-1776. Link:
  10. Pfeiffer M, Kotz R, Ledl T, Hauser G, Sluga M (2006) Prevalence of flat foot in preschool-aged children. Pediatrics 118: 634-639. Link:
  11. Novais EN, Millis MB (2012) Slipped capital femoral epiphysis: prevalence, pathogenesis, and natural history. Clin Orthop Relat Res 470: 3432-3438. Link:
  12. Kessler J, Koebnick C, Smith N, Adams A (2013) Childhood obesity is associated with increased risk of most lower extremity fractures. Clin Orthop Relat Res 471: 1199-1207. Link:
  13. Hardesty CK, Poe-Kochert C, Son-Hing JP, Thompson GH (2013) Obesity negatively affects spinal surgery in idiopathic scoliosis. Clin Orthop Relat Res 471: 1230-1235. Link:
  14. Sabharwal S, Zhao C, Sakamoto SM, McClemens E (2014) Do children with Blount disease have lower body mass index after lower limb realignment? J Pediatr Orthop 34: 213-218. Link:
  15. Nasreddine AY, Heyworth BE, Zurakowski D, Kocher MS (2013) A reduction in body mass index lowers risk for bilateral slipped capital femoral epiphysis. Clin Orthop Relat Res 471: 2137-2144. Link:
  16. Ogden CL, Flegal KM (2010) Changes in terminology for childhood overweight and obesity. Natl Health Stat Report 25: 1-5. Link:
  17. Varness T, Allen DB, Carrel AL, Fost N (2009) Childhood obesity and medical neglect. Pediatrics 123: 399-406. Link:
  18. Daniels SR (2009) Complications of obesity in children and adolescents. Int J Obes (Lond) 33: S60-65. Link:
  19. Trasande L, Chatterjee S (2009) The impact of obesity on health service utilization and costs in childhood. Obesity 17: 1749-1754. Link:
  20. Cawley J, Meyerhoefer C (2012) The medical care costs of obesity: an instrumental variables approach. J Health Econ 31: 219-230. Link:
  21. Chan G, Chen CT (2009) Musculoskeletal effects of obesity. Curr Opin Pediatr 21: 65-70. Link:
  22. Oude Luttikhuis H, Baur L, Jansen H, Shrewsbury VA, O’Malley C, et al. (2009) Interventions for treating obesity in children. Cochrane Database Syst Rev 1: CD001872. Link:
  23. Connelly JB, Duaso MJ, Butler G (2007) A systematic review of controlled trials of interventions to prevent childhood obesity and overweight: A realistic synthesis of the evidence. Public Health 121: 510-517. Link:
  24. Denzer C, Reithofer E, Wabitsch M, Widhalm K (2004) The outcome of childhood obesity management depends highly upon patient compliance. Eur J Pediatr 163: 99-104. Link:
  25. Pinelli L, Elerdini N, Faith MS, Agnello D, Ambruzzi A, et al. (1999) Childhood obesity: results of a multicenter study of obesity treatment in Italy. J Pediatr Endocrinol Metab 3: 795-799. Link:
  26. Reinehr T, Widhalm K, L’Allemand D, Wiegand S, Wabitsch M, et al. (2009) Two-year follow-up in 21,784 overweight children and adolescents with lifestyle intervention. Obesity 17: 1196-1199. Link:
  27. Epstein LH, Valoski A, Wing RR, McCurley J (1994) Ten-year outcomes of behavioral family-based treatment for childhood obesity. Health Psychol 13: 373-383. Link:
  28. Reinehr T, Wiegand S, Siegfried W, Keller KM, Widhalm K, et al. (2013) Comorbidities in overweight children and adolescents: do we treat them effectively? Int J Obes (Lond) 37: 493-499. Link:
  29. Campbell K, Waters E, O’Meara S, Summerbell C (2001) Interventions for preventing obesity in childhood. A systematic review. Obes Rev 2: 149-157. Link:
  30. Duncan DT, Hansen AR, Wang W, Yan F, Zhang J (2015) Change in Misperception of Child’s Body Weight among Parents of American Preschool Children. Child Obes 11: 384-393. Link:
  31. Han JC, Lawlor DA, Kimm SYS (2010) Childhood obesity. Lancet 375: 1737-1748. Link:
  32. Summerbell CD, Waters E, Edmunds LD, Kelly S, Brown T, et al. (2005) Interventions for preventing obesity in children. Cochrane database Syst Rev 12: CD001871. Link:
  33. Zwintscher NP, Azarow KS, Horton JD, Newton CR, Martin MJ (2013) The increasing incidence of adolescent bariatric surgery. J Pediatr Surg 48: 2401-2407. Link:
  34. Iqbal CW, Kumar S, Iqbal AD, Ishitani MB (2009) Perspectives on pediatric bariatric surgery: identifying barriers to referral. Surg Obes Relat Dis 5: 88-93. Link:
  35. Tsai WS, Inge TH, Burd RS (2007) Bariatric surgery in adolescents: recent national trends in use and in-hospital outcome. Arch Pediatr Adolesc Med 161: 217-221. Link:
  36. Inge TH, Zeller MH, Jenkins TM, Helmrath M, Brandt ML, et al. (2014) Perioperative outcomes of adolescents undergoing bariatric surgery: the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study. JAMA Pediatr 168: 47-53. Link:
  37. O’Brien PE, Sawyer SM, Laurie C, Brown WA, Skinner S, et al. (2010) Laparoscopic adjustable gastric banding in severely obese adolescents: a randomized trial. JAMA 303: 519-526. Link:
  38. Inge TH, Courcoulas AP, Jenkins TM, Michalsky MP, Helmrath MA, et al. (2016) Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. N Engl J Med 374: 113-123. Link:
© 2017 Pace GI, et al. This is an open-ammcess article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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