Sleep Apnea in COPD, the Role of Oxygen Saturation Index (ODI 4%) and the Ratio of Diaphragmatic Ultrasound

Meridj Amine*, Redouan Belala, Khaled Tlili and Yacine Djeghri

When COPD and obstructive sleep apnea-hypopnea syndrome coexist in one individual, it’s known as overlap syndrome. In individuals with COPD, diaphragmatic function may help anticipate nocturnal oxygen desaturation. Ultrasound has been used extensively to assess the diaphragm. We aimed to investigate the effects of ultrasound-measured diaphragm excursion and contractile capacity on percutaneous oxygen saturation in COPD.

Methods: We conducted a prospective, observational study from 2021 to 2024. A total of Sixty-one consecutive patients with spirometry-confirmed stable COPD were included after obtaining informed written consent. Demographic and clinical data, spirometric values, BMI, average night-time saturation, the Oxygen Desaturation Index (ODI) of 4% and Measurement of Diaphragm Thickness (TFdi) and Excursion (EXdi) were collected for analysis.

This is a prospective study conducted at Constantine Regional Military University Hospital.

Results: The average night-time saturation was 94,63 ± 2,16% (12 patients could not perform nocturnal oximetry), The average Oxygen Desaturation Index (ODI) was 4% 2,01 ± 2,65.

There was a significant positive correlation between diaphragmatic mobility (EXdi) and the average night-time saturation (r = 0,395, p = 0,005). However 

There was a significant negative correlation between diaphragmatic mobility and the average oxygen desaturation index (ODI 4 %) (r = -0,288, p = 0,045),

In our study on ‘objectified a significant negative correlation between 4% ODI and TFdi (r = - 0, 456 p = 0.001).

Conclusion: This study suggested a close relationship between the ultrasound parameters (TFdi, EXdi) assessed by ultrasonography in COPD on the one hand and the mean of night desaturation and (ODI) 4% on the other.

Keywords:

Published on: Nov 27, 2024 Pages: 32-39

Full Text PDF Full Text HTML DOI: 10.17352/aprc.000090
CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat