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    Tolerance to First-Line Immunotherapy in Elderly Patients with Advanced Solid Tumours

    DOI Logo 10.17352/ijocs.000066

    Published On: December 03, 2025 | Pages: 004 - 007

    Author(s): Angelina Towadros, Sandra Boles, Salman Anwar and Dalia Kamel*
    Aim of the study: This review examines how ageing-related changes in the immune system impact the response to immunotherapy and assesses the potential challenges to treatment tolerance in elderly patients. Methodology: This is a retrospective study of patients with advanced solid cancer treated at Blackrock and St Vincent Private Hospital with immunotherapy as first ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Preparation of Nano-drug Carrier by Microfluidic Technology for Oral Cancer Treatment

    DOI Logo 10.17352/ijocs.000065

    Published On: October 22, 2025 | Pages: 001 - 003

    Author(s): Tao Tang, Yuchen Liu, Xinkun Chen and Xueye Chen*
    In oral cancer therapy, traditional chemotherapeutic drugs cannot meet clinical needs due to poor targeting, low bioavailability, and severe side effects. Microfluidic technology, with precise fluid manipulation, enables efficient preparation of nanoparticulate drug carriers, realizing “precision fabrication” and “functional design” of nanocarriers. By adapting to ora ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Evaluation of the Relationship between Gubernaculum Dentis and Tooth Development with Cone Beam Computed Tomography

    DOI Logo 10.17352/2455-4634.000064

    Published On: December 06, 2024 | Pages: 009 - 016

    Author(s): Lale Rizeli and Ayşe Zeynep Zengin*

    ORCID Logo  0000-0002-4388-7751

    Aim: The Gubernaculum Dentis (GD) is a structure that serves as the eruption path for permanent teeth, extending from the tooth follicle to the gingiva and including the gubernacular cord. It plays a crucial role in the normal eruption process by providing a defined path for the tooth to emerge through the bone. Radiographically, GD is visible as a radiolucent area, b ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    An Easy Way of Identification and Protection of the Hypoglossal Nerve during Neck Dissection for Head and Neck Cancer

    DOI Logo 10.17352/2455-4634.000063

    Published On: October 23, 2024 | Pages: 006 - 008

    Author(s): D Deskos* and N Papadogeorgakis

    ORCID Logo  0000-0003-1234-0443

    Understanding the anatomical relationship between the Hypoglossal Nerve (HN) and the Facial Vein (FV) is crucial during neck dissections for head and neck cancer. The consistent placement of the HN beneath the FV provides a reliable anatomical landmark, aiding in the preservation of nerve function and reducing surgical complications. This paper reviews the anatomical ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Coronectomy of mandibular third molars with computer-assisted navigated system: A case report

    DOI Logo 10.17352/2455-4634.000062

    Published On: March 19, 2024 | Pages: 001 - 005

    Author(s): Pellegrino Gerardo, Angelino Claudia*, Elisabetta Vignudelli, Ferri Agnese and Felice Pietro

    ORCID Logo  0009-0006-2700-9066

    The present case report describes a successful surgical case of coronectomy of a fully impacted lower third molar in close relationship with the Inferior Alveolar Nerve (IAN) that was trapped in the furcation roots of the lower third molar. It was associated with a dentigerous cyst. Dynamic Navigation (DN) was used to minimize iatrogenic injuries to the IAN. Coronecto ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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