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Archives of Otolaryngology and Rhinology

    Introduction

    • Volume/IssueClick here
    • Review ProcessDouble Blind
      • Publication lead time3 - 4 weeks
      • Indexing statusYes; Purview
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      • Waiver policy for APCYes
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    • Articles digitally archived in PORTICO
    • Permanent article identifierDOI (Digital Object Identifier) We provide DOI to all published papers to facilitate higher citation and classification of articles.
      Peertechz Publisher ID: 10.17352
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    Editor-in-Chief

    Peter J Catalano

    Peter J Catalano
    Tufts University, USA
    Email: peter.catalano@steward.org
    Tel: +1- 617-999-2973; +1
    Fax: +1-617-789-5088

    More Info.

    Executive Editors

    Masatsugu Masuda
    Associate Professor
    Department of Otolaryngology
    Kyorin University School of Medicine
    Japan
    masoeur13@mac.com
    AOR

    Born

    Graduate from Keio University School of Medicine, Tokyo, Japan

    Resident in Dept of Otorhinolaryngology, Keio University School of Medicine, Tokyo, Japan

    Medical Staff in Otorhinolaryngology, Hiratsuka City Hospital, Kanagawa, Japan

    Medical Staff in Otorhinolaryngology, Keiyu Hospital, Kanagawa, Japan

    Medical Staff in Otorhinolaryngology, Kawasaki Municipal Hospital, Kanagawa, Japan

    Instructor in Otorhinolaryngology, Keio University School of Medicine, Tokyo, Japan

    Research staff in Basic Otology Research group (Professor Kaoru Ogawa), Keio University School of Medicine, Tokyo, Japan

    Medical staff in department of Otolaryngology of Saiseikai Kanagawa Hospital, Kanagawa, Japan

    Post-doctoral fellow in the Division of Otolaryngology-Head and Neck Surgery, University of California, San Diego

    Instructor in the Department of Otolaryngology, Kyorin University School of Medicine, Tokyo, Japan

    Associate Professor in the Department of Otolaryngology, Kyorin University School of Medicine, Tokyo, Japan

    Adjunct Lecturer in the Department of Otolaryngology, Keio University School of Medicine, Tokyo, Japan

    Professional website links:

    http://www.kyorin-u.ac.jp/univ/graduate/medicine/education/departments/otolaryngology/

    http://www.kyorin-u.ac.jp/hospital/clinic/surgery11/index.html

    Grant Details:

    2015-Present:  

    A grant-in-Aid for Scientific Research (C) [15K10761] from Ministry of Education, Culture, Sports, Science and Technology. “Changes of the auditory and equilibrium functions induced by optogenetic control of the stria vascularis function.”

    2011-2014:

    Grant-in Aid for Young Scientists (B) [23791930] from Ministry of Education, Culture, Sports, Science and Technology. “Artificial synapse formation for the implantable artificial organ of Corti.”

    List of Publications:

    1    Masuda, M., Goto, F., Hasegawa, T., Matsumoto, J., Kasakura-Kimura, N., Miyama, Y., Saito, K. & Kito, S. Transcranial magnetic stimulation for the treatment of vestibular decompensation. E-BENT, (in press).
    2    Watabe, T., Xu, M., Watanabe, M., Nabekura, J., Higuchi, T., Hori, K., Sato, M. P., Nin, F., Hibino, H., Ogawa, K., Masuda, M. & Tanaka, K. F. Time-controllable Nkcc1 knockdown replicates reversible hearing loss in postnatal mice. Sci Rep 7, 13605, doi:10.1038/s41598-017-13997-7 (2017).
    3    Sato, M. P., Higuchi, T., Nin, F., Ogata, G., Sawamura, S., Yoshida, T., Ota, T., Hori, K., Komune, S., Uetsuka, S., Choi, S., Masuda, M., Watabe, T., Kanzaki, S., Ogawa, K., Inohara, H., Sakamoto, S., Takebayashi, H., Doi, K., Tanaka, K. F. & Hibino, H. Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear. Front Mol Neurosci 10, 300, doi:10.3389/fnmol.2017.00300 (2017).
    4    Oishi, N., Yamada, H., Kanzaki, S., Kurita, A., Takiguchi, Y., Yuge, I., Asama, Y., Masuda, M. & Ogawa, K. Assessment of hyperacusis with a newly produced Japanese version of the Khalfa hyperacusis questionnaire. Acta Otolaryngol 137, 957-961, doi:10.1080/00016489.2017.1306654 (2017).
    5    Masuda, M., Li, Y., Pak, K., Chavez, E., Mullen, L. & Ryan, A. F. The Promoter and Multiple Enhancers of the pou4f3 Gene Regulate Expression in Inner Ear Hair Cells. Mol Neurobiol 54, 5414-5426, doi:10.1007/s12035-016-0060-7 (2017).
    6    Kasakura-Kimura, N., Masuda, M., Mutai, H., Masuda, S., Morimoto, N., Ogahara, N., Misawa, H., Sakamoto, H., Saito, K. & Matsunaga, T. WFS1 and GJB2 mutations in patients with bilateral low-frequency sensorineural hearing loss. Laryngoscope 127, E324-E329, doi:10.1002/lary.26528 (2017).
    7    Masuda, M., Mutai, H., Arimoto, Y., Nakano, A. & Matsunaga, T. A novel frameshift variant of COCH supports the hypothesis that haploinsufficiency is not a cause of autosomal dominant nonsyndromic deafness 9. Biochem Biophys Res Commun 469, 270-274, doi:10.1016/j.bbrc.2015.11.106 (2016).
    8        Masuda, M., Matsumoto, J., Nakamura, T., Matsuda, T., Naoyuki, K. & Saito, K. The impact of postoperative antrum pneumatization on hearing outcome after canal wall-down tympanoplasty with softwall reconstruction for cholesteatoma. Abstract for the 10th International Conference on Cholesteatoma,Edinburgh UK. J Laryngol Otol 130, S201-S202, https://doi.org/10.1017/S0022215116006228 (2016).
    9    Ryan, A. F., Ikeda, R. & Masuda, M. The regulation of gene expression in hair cells. Hear Res 329, 33-40, doi:10.1016/j.heares.2014.12.013 (2015).
    10    Masuda, M. & Kanzaki, J. Cause of idiopathic sudden sensorineural hearing loss: The stress response theory. World Journal of Otorhinolaryngology 3, 42-57, doi:10.5319/wjo.v3.i3.42 (2013).
    11    Masuda, M., Pak, K., Chavez, E. & Ryan, A. F. TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1. Dev Biol 372, 68-80, doi:10.1016/j.ydbio.2012.09.002 (2012).
    12    Masuda, M., Kanzaki, S., Minami, S., Kikuchi, J., Kanzaki, J., Sato, H. & Ogawa, K. Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss. Otol Neurotol 33, 1142-1150, doi:10.1097/MAO.0b013e3182635417 (2012).
    13    Masuda, M., Dulon, D., Pak, K., Mullen, L. M., Li, Y., Erkman, L. & Ryan, A. F. Regulation of POU4F3 gene expression in hair cells by 5' DNA in mice. Neuroscience 197, 48-64, doi:10.1016/j.neuroscience.2011.09.033 (2011).
    14    Wakabayashi, K., Fujioka, M., Kanzaki, S., Okano, H. J., Shibata, S., Yamashita, D., Masuda, M., Mihara, M., Ohsugi, Y., Ogawa, K. & Okano, H. Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea. Neurosci Res 66, 345-352, doi:10.1016/j.neures.2009.12.008 (2010).
    15    Taura, A., Taura, K., Choung, Y. H., Masuda, M., Pak, K., Chavez, E. & Ryan, A. F. Histone deacetylase inhibition enhances adenoviral vector transduction in inner ear tissue. Neuroscience 166, 1185-1193, doi:10.1016/j.neuroscience.2009.12.064 (2010).
    16    Choung, Y. H., Taura, A., Pak, K., Choi, S. J., Masuda, M. & Ryan, A. F. Generation of highly-reactive oxygen species is closely related to hair cell damage in rat organ of Corti treated with gentamicin. Neuroscience 161, 214-226, doi:10.1016/j.neuroscience.2009.02.085 (2009).
    17    Masuda, M., Tanaka, K. F., Kanzaki, S., Wakabayashi, K., Oishi, N., Suzuki, T., Ikenaka, K. & Ogawa, K. GFAP aggregates in the cochlear nerve increase the noise vulnerability of sensory cells in the organ of Corti in the murine model of Alexander disease. Neurosci Res 62, 15-24, doi:10.1016/j.neures.2008.05.005 (2008).
    18    Masuda, M., Inoue, Y., Tanosaki, R., Kanzaki, S. & Ogawa, K. Development of solitary plasmacytoma in the internal auditory canal and inner ear after allogeneic hematopoietic stem cell transplantation for plasma cell leukemia. Jpn J Clin Oncol 37, 701-703, doi:10.1093/jjco/hym079 (2007).
    19    Masuda, M., Nagashima, R., Kanzaki, S., Fujioka, M., Ogita, K. & Ogawa, K. Nuclear factor-kappa B nuclear translocation in the cochlea of mice following acoustic overstimulation. Brain Res 1068, 237-247, doi:10.1016/j.brainres.2005.11.020 (2006).
    20    Fujioka, M., Kanzaki, S., Okano, H. J., Masuda, M., Ogawa, K. & Okano, H. Proinflammatory cytokines expression in noise-induced damaged cochlea. J Neurosci Res 83, 575-583, doi:10.1002/jnr.20764 (2006).

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Transcranial magnetic stimulation for the treatment of vestibular decompensation. E-BENT, (in press).2    Watabe, T., Xu, M., Watanabe, M., Nabekura, J., Higuchi, T., Hori, K., Sato, M. P., Nin, F., Hibino, H., Ogawa, K., Masuda, M. & Tanaka, K. F. Time-controllable Nkcc1 knockdown replicates reversible hearing loss in postnatal mice. Sci Rep 7, 13605, doi:10.1038/s41598-017-13997-7 (2017).3    Sato, M. P., Higuchi, T., Nin, F., Ogata, G., Sawamura, S., Yoshida, T., Ota, T., Hori, K., Komune, S., Uetsuka, S., Choi, S., Masuda, M., Watabe, T., Kanzaki, S., Ogawa, K., Inohara, H., Sakamoto, S., Takebayashi, H., Doi, K., Tanaka, K. F. & Hibino, H. Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear. Front Mol Neurosci 10, 300, doi:10.3389/fnmol.2017.00300 (2017).4    Oishi, N., Yamada, H., Kanzaki, S., Kurita, A., Takiguchi, Y., Yuge, I., Asama, Y., Masuda, M. & Ogawa, K. Assessment of hyperacusis with a newly produced Japanese version of the Khalfa hyperacusis questionnaire. Acta Otolaryngol 137, 957-961, doi:10.1080/00016489.2017.1306654 (2017).5    Masuda, M., Li, Y., Pak, K., Chavez, E., Mullen, L. & Ryan, A. F. The Promoter and Multiple Enhancers of the pou4f3 Gene Regulate Expression in Inner Ear Hair Cells. Mol Neurobiol 54, 5414-5426, doi:10.1007/s12035-016-0060-7 (2017).6    Kasakura-Kimura, N., Masuda, M., Mutai, H., Masuda, S., Morimoto, N., Ogahara, N., Misawa, H., Sakamoto, H., Saito, K. & Matsunaga, T. WFS1 and GJB2 mutations in patients with bilateral low-frequency sensorineural hearing loss. Laryngoscope 127, E324-E329, doi:10.1002/lary.26528 (2017).7    Masuda, M., Mutai, H., Arimoto, Y., Nakano, A. & Matsunaga, T. A novel frameshift variant of COCH supports the hypothesis that haploinsufficiency is not a cause of autosomal dominant nonsyndromic deafness 9. Biochem Biophys Res Commun 469, 270-274, doi:10.1016/j.bbrc.2015.11.106 (2016).8        Masuda, M., Matsumoto, J., Nakamura, T., Matsuda, T., Naoyuki, K. & Saito, K. The impact of postoperative antrum pneumatization on hearing outcome after canal wall-down tympanoplasty with softwall reconstruction for cholesteatoma. Abstract for the 10th International Conference on Cholesteatoma,Edinburgh UK. J Laryngol Otol 130, S201-S202, https://doi.org/10.1017/S0022215116006228 (2016).9    Ryan, A. F., Ikeda, R. & Masuda, M. The regulation of gene expression in hair cells. Hear Res 329, 33-40, doi:10.1016/j.heares.2014.12.013 (2015).10    Masuda, M. & Kanzaki, J. Cause of idiopathic sudden sensorineural hearing loss: The stress response theory. World Journal of Otorhinolaryngology 3, 42-57, doi:10.5319/wjo.v3.i3.42 (2013).11    Masuda, M., Pak, K., Chavez, E. & Ryan, A. F. TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1. Dev Biol 372, 68-80, doi:10.1016/j.ydbio.2012.09.002 (2012).12    Masuda, M., Kanzaki, S., Minami, S., Kikuchi, J., Kanzaki, J., Sato, H. & Ogawa, K. Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss. Otol Neurotol 33, 1142-1150, doi:10.1097/MAO.0b013e3182635417 (2012).13    Masuda, M., Dulon, D., Pak, K., Mullen, L. M., Li, Y., Erkman, L. & Ryan, A. F. Regulation of POU4F3 gene expression in hair cells by 5' DNA in mice. Neuroscience 197, 48-64, doi:10.1016/j.neuroscience.2011.09.033 (2011).14    Wakabayashi, K., Fujioka, M., Kanzaki, S., Okano, H. J., Shibata, S., Yamashita, D., Masuda, M., Mihara, M., Ohsugi, Y., Ogawa, K. & Okano, H. Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea. Neurosci Res 66, 345-352, doi:10.1016/j.neures.2009.12.008 (2010).15    Taura, A., Taura, K., Choung, Y. H., Masuda, M., Pak, K., Chavez, E. & Ryan, A. F. Histone deacetylase inhibition enhances adenoviral vector transduction in inner ear tissue. Neuroscience 166, 1185-1193, doi:10.1016/j.neuroscience.2009.12.064 (2010).16    Choung, Y. H., Taura, A., Pak, K., Choi, S. J., Masuda, M. & Ryan, A. F. Generation of highly-reactive oxygen species is closely related to hair cell damage in rat organ of Corti treated with gentamicin. Neuroscience 161, 214-226, doi:10.1016/j.neuroscience.2009.02.085 (2009).17    Masuda, M., Tanaka, K. F., Kanzaki, S., Wakabayashi, K., Oishi, N., Suzuki, T., Ikenaka, K. & Ogawa, K. GFAP aggregates in the cochlear nerve increase the noise vulnerability of sensory cells in the organ of Corti in the murine model of Alexander disease. Neurosci Res 62, 15-24, doi:10.1016/j.neures.2008.05.005 (2008).18    Masuda, M., Inoue, Y., Tanosaki, R., Kanzaki, S. & Ogawa, K. Development of solitary plasmacytoma in the internal auditory canal and inner ear after allogeneic hematopoietic stem cell transplantation for plasma cell leukemia. Jpn J Clin Oncol 37, 701-703, doi:10.1093/jjco/hym079 (2007).19    Masuda, M., Nagashima, R., Kanzaki, S., Fujioka, M., Ogita, K. & Ogawa, K. Nuclear factor-kappa B nuclear translocation in the cochlea of mice following acoustic overstimulation. Brain Res 1068, 237-247, doi:10.1016/j.brainres.2005.11.020 (2006).20    Fujioka, M., Kanzaki, S., Okano, H. J., Masuda, M., Ogawa, K. & Okano, H. P
    More Info.
    Vittorio Calabrese
    Full Professor
    Biomedical and Biotechnological Sciences
    University of Catania
    Italy
    calabres92@gmail.com
    AOR

    Prof. Vittorio Calabrese, Graduated in Medicine on 1984 at the University of Catania, after specialization in Neurology, on 1988 at University of Catania, since 1996 was Researcher at the Department of Biochemistry, School of Medicine, University of Catania. By 2001 to date Prof. Calabrese is a Professor of Clinical Biochemistry at the School of Medicine and Surgery and actual Director of School of Specialization in Clinical Pathology and Clinical Biochemistry, University of Catania, University of Messina and University of Palermo. He is member of the Editorial Board of several high peer reviewed journals including: Journal of Neuroscience Research;  Neurochem Research;  Antioxidant Redox Signaling; Journal Neurochemistry;  Free Radical Biology Medicine; Current Neurovascular Disorders. He has been reviewer of national projects (Italian MIUR), and many foreign projects for foreign institutions. He has been member of the ASN Commission (05/E1) of the Italian MIUR for the year 2013 and 2014. His research focuses on the role of free radicals and antioxidants in human disease, particularly Alzheimer's disease and other brain disorders. His interest in identifying the most important antioxidants in the human diet and in developing novel antioxidants has critical bearing on treating human diseases and understanding how diet might cause or prevent them. Areas of his research interests includes role of Oxidative Stress and Mitochondrial dysfunction in Aging, Neurodegenerative disorders and Longevity; Proteomics and redox proteomics, Heat shock signal pathway Hormesis and Vitagenes in Neurodegeneration. The results of his researches have been reported in over 160 scientific papers published in outstanding international journals and widely cited (around 8500 total citations, around 5000 citations of the 10 most cited articles), for an HI value of 57 (ISI). He has deposited one patent (Nr. WO 2004/07883 A1 of  10.9.2004) for the use of curcumin and its derivatives in the treatment neurodegenerative disorders.

    Research Interest:

    Cellular Stress response, Vitagenes, Redoxomics, Lipidomics, Proteomics, Metabolomics, Neurodegenerative disorders, Diabetes, Meniere Diseases, Clinical Biochemistry and Clinical Pathology.

    URL: http://www.biometec.unict.it/docenti/vittorio.calabrese

    Grants: Human Proteomic Network 2014

    Skype ID: Vittorio.calabrese

    List of Publications:
    1.    Ragusa N., Sfogliano L., Calabrese V., and Rizza V. (1981). Effects of multivitamin treatment on the activity of rat liver triptophan pyrrolase during ethanol administration. Acta Vitaminologica et Enzimologica 3,(4), 199-204.
    2.    Calabrese V., Guerrera F., Avitabile M., Famà M., and Rizza V. (1984). Superoxide dismutase and reduced glutathione: possible defense operating in hyperoxic swimbladder of fish. In: Toxin, drugs and pollutans in marine animals. (eds. Bolis et al.) pp. 130-136. Springer-Verlag, Berlin.
    3.    Calabrese V., Fariello R.G. (1988). Regional distribution of malonaldehyde in mouse brain. Biochemical Pharmacology, 37,11, 2287-2288.
    4.    Rizza V., Lorefice R., Rizza N., and Calabrese V. (1992). Pharmacokinetics of L-carnitine in human subjects. In:  L-carnitine and its role in medicine: from function to therapy, (eds. Ferrari R., Dimauro S., Sherwood G.) pp. 63-77. Academic Press, New York.
    5.    Calabrese V., Renis M., Calderone A., Russo A., Barcellona M.L., Rizza V. (1996) Stress proteins and SH-groups in oxidant-induced cell damage after acute ethanol administration in rat. Free Radical Biology and Medicine 20, 391-397.
    6.    Renis M., Calabrese V., Russo A., Calderone A., Barcellona M.L., Rizza V. (1996) Nuclear DNA strand breaks during ethanol-induced oxidative stress in rat brain. FEBS Letters 390, 153-156.
    7.    Calabrese V., Renis M., Calderone A., Russo A., Reale S., Barcellona M.L., Rizza V. (1998) Stress proteins and SH-groups in oxidant-induced cell injury after chronic ethanol administration in rat. Free Radical Biology and Medicine 24, 1159-1167.
    8.    Calabrese V., Rizza V. (1999) Formation of propionate after short-term ethanol treatment and its interaction with the carnitine pool in rat. Alcohol 19, 169-176.
    9.    Pennisi G., Rapisarda G., Bella R., Calabrese V., Maertens de Noordhout A., Delwaide P.J. (1999) Absence of response to early transcranial magnetic stimulation in ischemic stroke patients. Stroke 30, 2666-2670.
    10.    Calabrese V., Rizza V. (1999) Effects of l-carnitine on the formation of fatty acid ethyl esters in brain and peripheral organs after short-term ethanol administration in rat. Neurochem. Res. 24, 79-84. 
    11.    Calabrese V., Testa D., Ravagna A., Bates T.E.,  A.M. Giuffrida Stella. (2000) HSP70 induction in the brain following ethanol administration in the rat: regulation by glutathione redox state. Biochem. Biophys. Res. Comm. 269, 397-400.
    12.    Calabrese V., Copani A., Testa D., Ravagna A., Spadaro F., Tendi E., Nicoletti V., A.M. Giuffrida Stella. (2000) Nitric oxide synthase induction in astroglial cell cultures: Effect on heat shock protein 70 synthesis and oxidant / antioxidant balance. J. Neurosci. Res. 60, 613-622.
    13.    Motterlini R., Foresti R., Bassi R., Calabrese V., Clark J.E., Green C.J. (2000) Endothelial Heme oxygenase-1 induction by hypoxia: modulation by inducible nitric oxide synthase (iNOS) and S-nitrosothiols. J. Biol. Chem. 275, 13613-13620.
    14.    Calabrese V., Scapagnini G., Catalano C., Dinotta F., Geraci D., Morganti P. (2000) Biochemical studies of a natural antioxidant isolated from rosemary and its application in cosmetic dermatology. Int. J. Tissue Reactions 22, 5-13.
    15.    Calabrese V., Bates T.E., Giuffrida Stella A.M. (2000) NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance. Neurochem Res. 65, 1315-1341.
    16.    Calandra C., Musumeci G., Mangiameli A., Calabrese V. (2000) Perception of alcoholism problem among young people between 13 and 30 years old. Eur. J. of Alcohol Studies 12, 85-89.
    17.    Scapagnini G., Dinotta F, Calabrese V. (2000) Oxidative stress and Neurodegenerative Disorders: The role of Vitamion E in Nutritional Neuroscience. Int. J. Immunopathol.  Immunopharmacology  1, 97-107.
    18.    Calabrese V., Scapagnini G., Catalano D., Dinotta F., Bates T.E., Calvani M, Giuffrida Stella A.M. (2001) Effects of acetyl-l-carnitine on the formation of fatty acid ethyl esters in brain and peripheral organs after short-term ethanol administration in rat. Neurochem. Res. 26, 167-174.
    19.    Calabrese, V., Scapagnini G., Catalano C., Bates T.E., Dinotta F., Micali G., A.M. Giuffrida Stella (2001) Induction of heat shock protein synthesis in human skin fibroblasts in response to oxidative stress: regulation by a natural antioxidant from rosemary extract. Int. J. Tissue Reactions 23, 51-58.
    20.    Calabrese, V., Scapagnini G., Giuffrida Stella A.M., Bates T.E., Clark J.B., (2001) Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity. Neurochem. Res. 26, 739-764.
    21.    Calabrese, V., Scapagnini G., Catalano C., Bates T.E., Geraci D., Pennisi G., Giuffrida Stella A.M. (2001) Induction of heat shock protein synthesis in human skin fibroblasts in response to oxidative stress: regulation by Vitamin E. Int. J. Tissue Reactions 23, 127-135.
    22.    Anello M, Ucciardello V, Piro S, Patane G, Frittitta L, Calabrese V, Giuffrida Stella AM, Vigneri R, Purrello F, Rabuazzo AM. (2001) Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio. Am. J. Physiol. Endocrinol. Metab. 281, E1082-1087.
    23.    Calabrese V., Scapagnini G., Ravagna A., Giuffrida Stella A., Butterfield A. (2002) Molecular chaperones and their roles in neural cell ifferentiation. Dev. Neurosci. 24, 40-56. 
    24.    Calabrese V., Scapagnini G., Ravagna A., Fariello R.G., Giuffrida Stella AM. and Abraham N. (2002) Regional distribution of heme oxygenase, hsp70, and glutathione in brain: relevance for endogenous oxidant / antioxidant balance and stress tolerance. J. Neurosci. Res. 68, 65-75.
    25.    Butterfield D.A., Castegna A., Drake J., Scapagnini G., Calabrese V. (2002) Vitamin E and neurodegenerative disorders associated with oxidative stress. Nutr. Neurosci. 4, 229-239.
    26.    Butterfield D., Castegna A., Pocernich C., Drake J., Scapagnini G., Calabrese V. (2002) Nutritional approaches to combat oxidative stress in Alzheimer's disease. J. Nutr. Biochem. 13, 444-461.
    27.    Scapagnini G., Foresti R., Calabrese V., Giuffirida Stella A.M., Green C.J., Motterlini R. (2002) Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers. Mol Pharmacol 61, 554-561.
    28.    Scapagnini G., Giuffrida Stella A.M., Abraham N.G., Alkon D., Calabrese V. (2002) Differential expression of Heme oxygenase-1 in rat brain by endotoxin (LPS). In: Heme Oxygenase in Biology and Medicine (Abraham et al., eds.) pp. 121-134, Kluwer Academic Plenum Publisher, N.Y.
    29.    Calabrese V., Scapagnini G., Ravagna A., Bella R., Foresti R., Bates T.E., Giuffrida Stella A.M., Pennisi G. (2002) Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in CSF protein nitrotyrosine, S-nitrosothiols and with changes in glutathione levels. J. Neurosci. Res. 70, 580-587.
    30.    Scapagnini G., D'Agata V., Calabrese V., Pascale A., Colombrita C., Alkon D., Cavallaro S. (2002) Gene expression profiles of heme oxygenase isoforms in the rat brain. Brain Res. 954, 51-59.
    31.    Calabrese V., Scapagnini G., Latteri S., Colombrita C., Ravagna A., Catalano C., Pennisi G., Calvani M., Butterfield D.A. (2002) Long-term ethanol administration enhances age-dependent modulation of redox state in different brain regions in the rat: protection by acetyl carnitine. Int. J. Tissue Reactions 24, 97-104.
    32.    Scapagnini G., Ravagna A., Bella R., Colombrita C., Pennisi G., Calvani M., Alkon D., Calabrese V. (2002) Long-term ethanol administration enhances age-dependent modulation of redox state in brain and peripheral organs of rat: protection by acetyl carnitine. Int. J. Tissue Reactions. 24, 89-96.
    33.    Calabrese V., Scapagnini G., Latteri S., Butterfield D.A., Scapagnini U. Heme oxygenase, carbon monoxide and Cellular Stress Response in the Nervous System: The good and the enigmatic. (2002) Neurochemistry News 2, 57-60.
    34.    Colombrita C., Calabrese V., Stella A.M., Mattei F., Alkon D.L., Scapagnini G. (2003) Regional rat brain distribution of heme oxygenase-1 and manganese superoxide dismutase mRNA: relevance of redox homeostasis in the aging processes. Exp. Biol. Med. 228, 517-524. 
    35.    Catania M.V., Giuffrida R., Seminara G., Barbagallo G., Aronica E., Gorter J.A., Dell'Albani P., Ravagna A., Calabrese V., Giuffrida-Stella A.M. (2003) Upregulation of neuronal nitric oxide synthase in in vitro stellate astrocytes and in vivo reactive astrocytes after electrically induced status epilepticus. Neurochem. Res 28, 607-615.
    36.    Calabrese, V., Scapagnini, G., Ravagna, A., Bella, R., Butterfield, D.A., Calvani, M., Pennisi, G., Giuffrida Stella, A.M.. (2003). Disruption of thiol homeostasis and nitrosative stress in the cerebrospinal fluid of patients with active multiple sclerosis: evidence for a protective role of acetylcarnitine. Neurochem. Res. 28, 1321-1328.
    37.    Drake J., Sultana R., Aksenova M., Calabrese V., Butterfield DA. (2003). Elevation of mitochondrial glutathione by gamma-glutamylcysteine ethyl ester protects mitochondria against peroxynitrite-induced oxidative stress. J. Neurosci. Res. 74, 917-927.
    38.    Calabrese V., Scapagnini G., Colombrita C., Ravagna A., Pennisi G., Giuffrida Stella A.M., Galli F., Butterfield DA. (2003). Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: A nutritional approach. Amino Acids 25, 437-444.
    39.    Calabrese V., Butterfield D.A., Giuffrida Stella A.M. (2003) Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease. Italian Journal of Biochemistry 52, 72-76.
    40.    Calabrese V., Scapagnini G., Ravagna A., Colombrita C., Spadaro F., Butterfield D.A., Giuffrida Stella A.M. (2004). Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state. Mech. Age Dev. 125, 325-335.
    41.    Poon H.F., Calabrese V., Scapagnini G., Butterfield D.A. (2004) Free radicals: key to brain aging and heme oxygenase as a cellular response to oxidative stress. J. Gerontology A 59, 478-493.
    42.    Poon H.F., Calabrese V., Scapagnini G., Butterfield D.A. (2004). Free radicals and brain aging. Clin. Geriatr. Med. 20, 329-359.
    43.    Pocernich C.B., Sultana R., Hone E., Turchan J., Martins R.N., Calabrese V., Nath A., Butterfield D.A. (2004). Effects of apolipoprotein E on the human immunodeficiency virus protein tat in neuronal cultures and synaptosomes. J. Neurosci. Res. 77, 532-539.
    44.    Poon H.F., Joshi G., Sultana R., Farr S.A., Banks W.A., Morley J.E., Calabrese V., Butterfield D.A. (2004). Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice. Brain Res. 1018, 86-96.
    45.    Calabrese V., Giuffrida Stella AM, Butterfield DA, Scapagnini G. (2004) Redox Regulation in Neurodegeneration and Longevity: Role of the Heme Oxygenase and HSP70 Systems in Brain Stress Tolerance. Antioxid Redox Signal. 6, 895-913.
    46.    Scapagnini G, Butterfield DA, Colombrita C, Sultana R, Pascale A, Calabrese V. (2004) Ethyl Ferulate, a Lipophilic Polyphenol, Induces HO-1 and Protects Rat Neurons Against Oxidative Stress. Antioxid Redox Signal. 6, 811-818.
    47.    Calabrese V., Boyd-Kimball D, Scapagnini G, Butterfield DA. (2004) Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes. In Vivo. 18, 245-268.
    48.    Calabrese V., Calvani M, Butterfield DA. (2004). Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat. Arch. Biochem. Biophys. 431, 271-278.
    49.    Calabrese V., Ravagna A., Colombrita C., Guagliano E., Scapagnini G., Calvani M., Butterfield D.A., Giuffrida Stella A.M. (2005) Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2. J. Neuroscience Research 79, 509-521.
    50.    Sultana R., Ravagna A., Mohmmad-Abdul H., Calabrese V., Butterfield D.A. (2005) Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J. Neurochem. 92, 749-758. 
    51.    Pocernich C., Boyd-Kimball D., Poon F., Thongboonkerd V., Lynn B.C., Calabrese V.,  Nath A., Butterfield D.A. (2005) Proteomic analysis of human Astrocytes expressing the HIV protein TAT. Brain Res. (Mol Brain Res). 133, 307-316.
    52.    Poon H.F., Hensley K., Thingboonkerd V., Merchant M.L., Lynn B.C., Pierce W.M., Knlein J.B., Calabrese V., Butterfeild D.A. (2005) Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. Free Rad. Biol. Med. 39, 453-462.
    53.    Perluigi M., Poon H.F., Hensley K., Pierce W.M., Klein J.B., Calabrese V., De Marco C., Butterfield D.A. (2005) .Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice-A model of familial amyotrophic lateral sclerosis. Free Radic. Biol. Med. 38, 960-968.
    54.    Poon H.F., Frasier M., Shreve N., Calabrese V., Wolozin B., Butterfield D.A. (2005) Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease. Neurobiol. Dis. 18, 492-498.
    55.    Calabrese V., Ravagna A., Scapagnini G., Catalano C., Pennisi G., Butterfield D.A., Giuffrida Stella A.M. (2005) Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich Ataxia. J. Neurol Sci. 233, 145-162.
    56.    Calabrese V., Colombrita C., Guagliano E., Sapienza M., Ravagna A., Tomaselli G., Cardile V. Scapagnini G., Butterfield D.A., Giuffrida Stella A.M., and Rizzarelli E.. (2005) Protective effect of carnosine during nitrosative stress in astroglial cell cultures. Neurochem. Res. 30, 797-807. 
    57.    Perluigi M., Poon H.F., Maragos W., Pierce WM., JB Klein JB, Calabrese V., Cini C., De Marco C., Butterfield D.A., (2005). Proteomic Analysis of Protein Expression and Oxidative Modification in R6/2 Transgenic Mice--A Model of Huntington's Disease. Molecular and Cellular Proteomics, 4, 1849-1861.
    58.    Poon H.F., Shepherd H.M., Reed T., Calabrese V., Giuffrida-Stella A.M., Pennisi G., Cai J., Pierce W.M., ; Klein J.B., Butterfield D.A: (2006) Proteomics Analysis Provides Insight into Caloric Restriction-Mediated Reduced Oxidation and Altered Expression of Brain Proteins Associated with Age-related Impaired Cellular Processes: Mitochondrial Dysfunction, Glutamate Dysregulation and Impaired Protein Synthesis. Neurobiology of Aging 27, 1020-1034.
    59.    Calabrese V., Pennisi G., Calvani M., Giuffrida Stella A.M., Butterfield D.A., Mancuso C. (2006) Heme Oxygenase As Therapeutic Funnel in Nutritional Redox Homeostasis and Cellular Stress Response: Role of Acetylcarnitine. In: Heat Shock Protein in Neural Cells, Christiane Ritcher-Landsberg Eds., Eurekah.com
    60.    Calabrese V., Colombrita C., Scapagnini G., Calvani M., Giuffrida Stella AM., Butterfield D.A. (2006) Acetylcarnitine and cellular stress response: role in nutritional redox homeostasis and regulation of longevity genes. J. Nutr. Biochemistry 17,73-88.
    61.    Perluigi M., Joshi G, Sultana R., Calabrese V., De Marco C., Coccia R., Butterfield D.A. (2006) In vivo protection by the xanthate tricyclodecan-9-yl-xanthogenate against amyloid beta-peptide (1-42)-induced oxidative stress. Neuroscience 138, 1161-1170.
    62.    Joshi G., Perluigi M., Sultana R., Agrippino R., Calabrese V.,  Butterfield D.A. (2006) In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or  Fe(2+)/H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders. Neurochem. Int. 48,:318-327.
    63.    Calabrese V., Butterfield D.A., Scapagnini G., Stella A.M., Maines M.D. (2006) Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity. Antioxid Redox Signal. 8, 444-477. 
    64.    Lodi R., Tonon C., Calabrese V., Schapira A.H. (2006) Friedreich's Ataxia: From Disease Mechanisms to Therapeutic Interventions. Antioxid Redox Signal. 8, 438-443.
    65.    Calabrese V., Colombrita C., Sultana R., Scapagnini G., Calvani M., Butterfield D.A., Stella A.M. (2006) Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function. Antioxid Redox Signal. 8, 404-416.
    66.    Scapagnini G., Colombrita C., Amadio M., D'Agata V., Arcelli E., Sapienza M., Quattrone A., Calabrese V. (2006) Curcumin activates defensive genes and protects neurons against oxidative stress. Antioxid Redox Signal. 8, 395-403.
    67.    Calabrese V., Maines M.D. (2006) Antiaging medicine: antioxidants and aging. Antioxid Redox Signal. 8, 362-364.
    68.    Poon H.F., Calabrese V., Calvani M., Butterfield D.A. (2006) Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by L-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress. Antioxid Redox Signal. 8, 381-394.
    69.    Abdul H.M., Calabrese V., Calvani M., Butterfield D.A. (2006) Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease. J. Neurosci. Res. 84, 398-408.
    70.    Perluigi M., Joshi G., Sultana R., Calabrese V., De Marco C., Coccia R., Cini C., Butterfield D.A. (2006) In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress. J. Neurosci. Res. 84, 418-426.
    71.    Mancuso C., Perluigi M., Cini C., De Marco C., Giuffrida Stella A.M., Calabrese V., (2006) Heme oxygenase and cyclooxygenase in the central nervous system: A functional interplay. J. Neurosci. Res. 84, 1385-1391.
    72.    Calabrese V., Sultana R., Scapagnini G., Guagliano E., Sapienza M., Bella R., Kanski J., Pennisi G., Mancuso C., Stella A.M., Butterfield D.A. (2006) Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. Antioxid. Redox. Signal. 8, 1975-1986.
    73.    Mancuso C., Pani G., Calabrese V. (2006) Bilirubin: an endogenous scavenger of nitric oxide and reactive nitrogen species. Redox Rep. 11, 207-213.
    74.    Mancuso C., Scapagnini G., Curro D., Giuffrida Stella A.M., De Marco C., Butterfield D.A., Calabrese V. (2007) Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders. Front Biosci. 12, 1107-1123.
    75.    Calabrese V., Guagliano E., Sapienza M., Panebianco M., Calafato S., Puleo E., Pennisi G., Mancuso C., Butterfield A.D., Giuffrida Stella A.M. (2007) Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes. Neurochem Research 32, 757-773.
    76.    Calabrese V., Mancuso C., Ravagna A., Perluigi M., Cini C., De Marco C., Butterfield D.A., Giuffrida Stella A.M. (2007) In vivo induction of heat shock proteins in the substantia nigra following L-DOPA administration is associated with increased activity of mitochondrial complex I and nitrosative stress in rats: regulation by glutathione redox state. J. Neurochem. 101, 709-717.
    77.    Piroddi M., Depunzio I., Calabrese V., Mancuso C., Aisa C.M., Binaglia L., Minelli A., Butterfield A.D., Galli F. (2007) Oxidatively-modified and glycated proteins as candidate pro-inflammatory toxins in uremia and dialysis patients. Amino Acids 32, 573-592.
    78.     Calabrese V. (2007) Highlight Commentary on “Redox proteomics analysis of oxidatively 3 modified proteins in G93A–SOD1 transgenic mice—A model of 4 familial amyotrophic lateral sclerosis”. Free Radical Biol. Med. 43, 160-162.
    79.    Calabrese V., Mancuso C., Calvani M., Rizzarelli E., Butterfield D.A., Giuffrida Stella A.M.. (2007) Nitric Oxide in the CNS: Neuroprotection versus Neurotoxicity. Nature Neuroscience 8, 766-775.
    80.    Calabrese V., Mancuso C., Sapienza M., Puleo E., Calafato S., Cornelius C., Finocchiaro M., Mangiameli A., Di Mauro M., Stella A.M., Castellino P. (2007) Oxidative stress and cellular stress response in diabetic nephropathy. Cell Stress Chaperones 12, 299-306.
    81.    Athanasiou A., Clarke A.B., Turner A.E, Kumaran N.M., Vakilpour S., Smith P.A., Bagiokou D., Bradshaw T.D, Westwell A.D, Fang L., Lobo D.N, Constantinescu C.S, Calabrese V., Loesch A. Alexander S.P, Clothier R.H, Kendall D.A, Bates T.E. (2007). Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications. 364, 131-137.
    82.    Mancuso C, Bates TE, Butterfield DA, Calafato S, Cornelius C, De Lorenzo A, Dinkova Kostova AT, Calabrese V. (2007) Natural antioxidants in Alzheimer's disease. Expert Opin Investig Drugs. 16, 1921-1931.
    83.    Calabrese V., Cornelius C., Mancuso C., Pennisi G., Calafato S., Bellia F., Bates T.E, Giuffrida Stella A.M., Schapira T., Dinkova Kostova A.T., Rizzarelli E. (2008) Cellular Stress Response: A Novel Target for Chemoprevention and Nutritional Neuroprotection in Aging, Neurodegenerative Disorders and Longevity. Neurochem. Res. 33, 2444-2471.
    84.    Mancuso C., Capone C., Ranieri S.C., Fusco S., Calabrese V., Eboli M.L., Preziosi P., Galeotti T., Pani G. (2008) Bilirubin as an endogenous modulator of neurotrophin redox signaling. J. Neurosci Res. 86, 1212-1230.
    85.    Calabrese V., Signorile A., Cornelius C., Mancuso C., Scapagnini G., Ventimiglia B., Ragusa N., Dinkova-Kostova A. (2008)  Practical approaches to investigate redox regulation of heat shock protein expression and intracellular glutathione redox state. Methods Enzymol. 441, 83-110.
    86.    Calabrese V., Bates T.E., Mancuso C., Cornelius C., Ventimiglia B., Cambria M.T., Di Renzo L., De Lorenzo A., Dinkova-Kostova A.T. (2008) Curcumin and the cellular stress response in free radical-related diseases. Mol. Nutr. Food Res. 52, 1062-1073.
    87.    Calabrese V., Calafato S., Puleo E., Cornelius C., Sapienza M., Morganti P., Mancuso C. (2008) Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes. Clin. Dermatol. 26, 358-363.
    88.    Di Renzo L., Bertoli A., Bigioni M., Del Gobbo V., Premrov M.G., Calabrese V., Di Daniele N., De Lorenzo A. (2008) Body composition and -174G/C interleukin-6 promoter gene polymorphism: association with progression of insulin resistance in normal weight obese syndrome. Curr. Pharm. Des. 14, 2699-2706.
    89.    Calabrese V., Ientile R., Cornelius C., Scalia M., Cambria M.T., Ventimiglia B., Pennini G., Mancuso C., Butterfield D.A. (2008) Nutritional redox homeostasis and cellular stress response: Differential role of homocysteine and acetylcarnitine. In: Dietary modulation of cell sygnaling pathways. Surh Y.J., Dong Z., Cadenas E., Packer L. Eds. CRC Press, New York, N.Y. (USA)
    90.    Calabrese V., Calafato S., Cornelius C., Mancuso C., Dinkova-Kostova A. (2008) Heme oxygenase: A master vitagene involved in cellular stress response In: Enzymes and the Cellular Fight Against Oxidation. AM Eleuteri ed., Research Signpost 37/661 (2), Fort P.O., Trivandrum-695 023, Kerala, India. ISBN: 978-81-308-0239-8.
    91.    Calabrese V., Mancuso C., Cornelius C., Calafato M., Ventimiglia B., Butterfield D.A., Dinkova-Kostova A.T., Rizzarelli E. (2008) Reactive nitrogen species and cellular stress tolerance in aging and neurodegeneration: Role of vitagenes. In: Free Radical Pathophysiology, Alvarez S. and Evelson P. eds., 37/661 (2), pp. 345-367. Transworld Research Network, Kerala, India. ISBN 978-81-7895-311-3.
    92.    Calabrese V., Butterfield D.A., Stella A.M. (2008) Aging and oxidative stress response in the CNS. In: Development and Aging Changes in the Nervous System. Handbook of Neurochemistry and Molecular Neurobiology, Lajtha Abel, Perez-Polo J. Regino, Rossner Steffen (Eds.), 3rd ed., pp. 128-234. ISBN: 978-0-387-32670-2.
    93.    Calabrese V., Cornelius C., Mancuso C., Ientile R., Giuffrida Stella A.M., Butterfield D.A. (2008) Redox Homeostasis and Cellular Stress Response in Aging and Neurodegeneration. In: Free Radical and Antioxidant Protocols (2nd Edition), Uppu, R.M.; Murthy, S.N.; Pryor, W.A.; Parinandi, N.L. (Eds.), Humana Press, LA, USA.
    94.    Calabrese V., Perluigi M., Cornelius C., Coccia R., Di Domenico F., Mancuso C., Pennisi G., Dinkova-Kostova A.T. (2009) Phenolics in aging and neurodegenerative disorders. In: Phenolic Compounds of Plant Origin and Health: The Biochemistry behind their Nutritional and Pharmacological Value", C.G. Fraga Ed., Wiley & Sons, NY. USA.
    95.    Calabrese V., Cornelius C., Dinkova-Kostova A.T., Calabrese E.J. (2009) Vitagenes, cellular stress response and acetylcarnitine: relevance to hormesis. Biofactors 35, 146-160.
    96.    Calabrese V., Cornelius C., Mancuso C., Barone E., Calafato S., Bates T., Rizzarelli E., Kostova A.T. (2009) Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases. Front Biosci. 14, 376-397.
    97.    Bellia F., Calabrese V., Guarino F., Cavallaro M., Cornelius C., De Pinto V., Rizzarelli E. (2009) Carnosinase Levels in Aging Brain: Redox State Induction and Cellular Stress Response. Antioxid Redox Signal. 11, 2759-2775.  
    98.    Calabrese V., Cornelius C., Rizzarelli E., Owen J.B., Dinkova-Kostova A.T., Butterfield D.A. (2009) Nitric oxide in cell survival: a Janus molecule. Antioxid. Redox. Signal. 11, 2717-2739.
    99.    Calabrese V., Cornelius C., Trovato A., Cambria M.T., Lo Cascio M.S., Di Rienzo L., Condorelli D., De Lorenzo A., Calabrese E.J. (2010) The hormetic role of dietary antioxidants in free radical-related diseases. Curr. Pharm. Des. 16: 8778-83.
    100.    Calabrese V, Cornelius C, Mancuso C, Lentile R, Stella AM, Butterfield DA. (2010) Redox homeostasis and cellular stress response in aging and neurodegeneration. Methods Mol. Biol. 610, 285-308.
    101.    De Lorenzo A, Noce A, Bigioni M, Calabrese V., Della Rocca DG, Di Daniele N, Tozzo C,   Di Renzo L. (2010) The effects of Italian Mediterranean organic diet (IMOD) on health status. Curr Pharm Des. 16: 814-824.
    102.    Calabrese V., Cornelius C., Dinkova-Kostova AT., Calabrese E.J., Mattson MP. (2010) Cellular stress responses, the hormesis paradigm and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid Redox Signal. 13, 1763-1811.
    103.    Di Domenico F, Perluigi M, Butterfield DA, Cornelius C, Calabrese V. (2010) Oxidative Damage in Rat Brain During Aging: Interplay Between Energy and Metabolic Key Target Proteins. Neurochem Res. 35, 2184-2192.
    104.    Perluigi M, Di Domenico F, Giorgi A, Schininà ME, Coccia R, Cini C, Bellia F, Cambria MT, Cornelius C, Butterfield DA, Calabrese V. (2010) Redox proteomics in aging rat brain: Involvement of mitochondrial reduced glutathione status and mitochondrial protein oxidation in the aging process. J Neurosci Res. 88, 3498-3507.
    105.    Calabrese V., Cornelius C., Giuffrida A.M., Calabrese E.J. (2010) Cellular stress responses, mitostress and carnitine insufficiencies  as critical determinants in aging and neurodegenerative disorders: role of hormesis and vitagenes. Neurochem Res. 35, 1880-1915.
    106.    Calabrese V., Cornelius C., Maiolino L., Luca M., Chiaramonte R., Toscano M.A., Serra A. (2010) Oxidative stress, redox homeostasis and cellular stress response in ménière's disease: role of vitagenes. Neurochem Res. 35, 2208-2217.
    107.    Calabrese EJ, Mattson MP, Calabrese V. (2010) Dose response biology: the case of resveratrol. Hum Exp Toxicol. 29, 1034-1037.
    108.    Calabrese EJ, Mattson MP, Calabrese V. (2010) Resveratrol commonly displays hormesis:occurrence and biomedical significance. Hum Exp Toxicol. 29980-1015.
    109.    Cambria MT, Ragusa S, Calabrese V, Cambria A. (2011) Enhanced Laccase Production in White-Rot Fungus Rigidoporus lignosus by the Addition of Selected Phenolic and Aromatic Compounds. Appl Biochem Biotechnol. 163: 415-422.
    110.    Di Paola R., Impellizzeri D., Trovato Salinaro A., Mazzon E., Bellia F., Cavallaro M., Cornelius C., Vecchio G., Calabrese V., Rizzarelli E, Cuzzocrea S. Administration of carnosine in the treatment of acute spinal cord injury. (2011). Biochem Pharm  82, 1478-1489.
    111.    Pennisi G. , Cornelius C., Cavallaro M.M., Trovato Salinaro A., Cambria M.T., Pennisi M., Bella R., Milone P., Ventimiglia B., Migliore M.R., Di Renzo L., De Lorenzo A., Calabrese V. (2011). Redox regulation of cellular stress response in multiple sclerosis. Biochem Pharm  82, 1490-1499.
    112.    Scapagnini G, Caruso C, Calabrese V. Therapeutic Potential of Dietary Polyphenols against Brain Ageing and Neurodegenerative Disorders. (2011) Adv Exp Med Biol. 698: 27-35.
    113.    Calabrese V., Cornelius C., Cuzzocrea S., Iavicoli I., Rizzarelli E., Calabrese EJ. (2011) Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity.  Mol Aspects of Med. 32: 279-304. 
    114.    Bellia F., Vecchio G., Cuzzocrea S., Calabrese V., Rizzarelli E. (2011) Neuroprotection in oxidative driven diseases by carnosine. Mol Aspects of Med. 32: 258-266
    115.    Siciliano R, Barone E, Calabrese V, Rispoli V, Butterfield DA, Mancuso C. (2011) Experimental Research On Nitric Oxide And The Therapy Of Alzheimer Disease: A Challenging Bridge. CNS Neurol  Disord Drug Targets. 10: 766-776.
    116.    Zhang Y, Ahn YH, Benjamin IJ, Honda T, Hicks RJ, Calabrese V, Cole PA, Dinkova-Kostova AT. (2011) HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway. Chem Biol. 18:1355-1361. 
    117.    Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ. (2012) Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity. Biochim Biophys Acta. 1822: 753-783. 
    118.    Di Renzo L, Bianchi A, Saraceno R, Calabrese V, Cornelius C, Iacopino L, Chimenti S, De Lorenzo A. (2012)  -174G/C IL-6 gene promoter polymorphism predicts therapeutic response to TNF-α blockers. Pharmacogenet Genomics  22: 134-142. 
    119.    Calabrese V, Cornelius C, Leso V, Trovato-Salinaro A, Ventimiglia B, Cavallaro M, Scuto M, Rizza S, Zanoli L, Neri S, Castellino P.  (2012) Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes. Biochim Biophys Acta. 1822: 729-736.
    120.    Calabrese EJ, Iavicoli I, Calabrese V. (2012)  Hormesis: why it is important to biogerontologists. Biogerontology.13: 215-235. 
    121.    Cornelius C, Perrotta R, Graziano A, Calabrese EJ, Calabrese V. (2013) Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a "chi". Immun. Ageing. 10:15. doi:10.1186/1742-4933-10-15.
    122.    Cornelius C, Crupi R, Calabrese V, Graziano A, Milone P, Pennisi G, Radak Z, Calabrese EJ, Cuzzocrea S. (2013) Traumatic Brain Injury: Oxidative Stress and Neuroprotection. Antioxid Redox Signal. 19: 836-853. 
    123.    Calabrese EJ, Calabrese V. (2013) Low dose radiation therapy (LD-RT) is effective in the treatment of arthritis: animal model findings. Int J Radiat Biol. 89: 287-294. 
    124.    Calabrese EJ, Calabrese V. (2013)  Reduction of arthritic symptoms by low dose radiation therapy (LD-RT) is associated with an anti-inflammatory phenotype. Int J Radiat Biol. 89: 278-286. 
    125.    Calabrese EJ, Iavicoli I, Calabrese V. (2013)  Hormesis: its impact on medicine and health. Hum Exp Toxicol. 32: 120-152.
    126.    Zhang Y., Dayalan Naidu S., R.V. Kostov, A. Pheely, V. Calabrese and A.T. Dinkova-Kostova (2013) Sulfhydryl-Reactive Phytochemicals as Dual Activators of Transcription Factors NRF2 and HSF1. In: D. R. Gang (ed.), 50 Years of Phytochemistry Research, Recent Advances in Phytochemistry 43, DOI 10.1007/978-3-319-00581-2_6, © Springer International Publishing (Switzerland).
    127.    Mancuso C, Santangelo R, Calabrese V. (2013) The heme oxygenase/biliverdin reductase  system: a potential drug target in Alzheimer’s disease. J Biol Regul Homeost Agents. 27: 75-87.
    128.    Cornelius C, Trovato Salinaro A, Scuto M, Fronte V, Cambria MT, Pennisi M, Bella R, Milone P, Graziano A, Crupi R, Cuzzocrea S, Pennisi G, Calabrese V. (2013) Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes. Immun Ageing 10:41. doi: 10.1186/1742-4933-10-41.
    129.    Cornelius C, Graziano A, Calabrese EJ, Calabrese V. (2013) Hormesis and vitagenes in aging and longevity: mitochondrial control and hormonal regulation. Horm Mol Biol Clin Investig. 16:73-89.
    130.    Edrey YH, Oddo S, Cornelius C, Caccamo A, Calabrese V, Buffenstein R. (2014) Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents. J Neurosci Res. 92: 195-205.
    131.    Davinelli S, Calabrese V, Zella D, Scapagnini G. (2014) Epigenetic nutraceutical diets in Alzheimer's disease. J Nutr Health Aging. Dec;18(9):800-5. doi: 10.1007/s12603-014-0520-6. PubMed PMID: 25389957.
    132.    Scapagnini G, Davinelli S, Kaneko T, Koverech G, Koverech A, Calabrese EJ, Calabrese V. (2014) Dose response biology of resveratrol in obesity. J Cell Commun Signal. 8: 385-391.
    133.    Calabrese V, Scapagnini G, Davinelli S, Koverech G, Koverech A, De Pasquale C, Salinaro AT, Scuto M, Calabrese EJ, Genazzani AR. (2014) Sex hormonal regulation and hormesis in aging and longevity: role of vitagenes. J Cell Commun Signal. 8: 369-384.
    134.    Davinelli S, Scapagnini G, Denaro F, Calabrese V, Benedetti F, Krishnan S, Curreli S, Bryant J, Zella D. (2014) Altered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat. Biogerontology. 15: 449-461.
    135.    Cornelius C, Koverech G, Crupi R, Di Paola R, Koverech A, Lodato F, Scuto M, Salinaro AT, Cuzzocrea S, Calabrese EJ, Calabrese V. (2014) Osteoporosis and Alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling. Front Pharmacol. 5:120. doi:10.3389/fphar.2014.00120. eCollection 2014.
    136.    Trovato Salinaro A, Cornelius C, Koverech G, Koverech A, Scuto M, Lodato F, Fronte V, Muccilli V, Reibaldi M, Longo A, Uva MG, Calabrese V. (2014) Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer's disease. Front Pharmacol. 5:129. doi:10.3389/fphar.2014.00129. eCollection 2014.
    137.    Currò M, Trovato-Salinaro A, Gugliandolo A, Koverech G, Lodato F, Caccamo D, Calabrese V, Ientile R. (2015) Resveratrol protects against homocysteine-induced cell damage via cell stress response in neuroblastoma cells. J Neurosci Res. 93: 149-156.
    138.    Davinelli S, Scapagnini G, Denaro F, Calabrese V, Benedetti F, Krishnan S, Curreli S, Bryant J, Zella D. (2014) Altered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat. Biogerontology. 15: 449-461.
    139.    Cornelius C, Koverech G, Crupi R, Di Paola R, Koverech A, Lodato F, Scuto M, Salinaro AT, Cuzzocrea S, Calabrese EJ, Calabrese V. (2014) Osteoporosis and Alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling. Front Pharmacol. 5:120. doi:10.3389/fphar.2014.00120. eCollection 2014.
    140.    Trovato Salinaro A, Cornelius C, Koverech G, Koverech A, Scuto M, Lodato F, Fronte V, Muccilli V, Reibaldi M, Longo A, Uva MG, Calabrese V. (2014) Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer's disease. Front Pharmacol. 5:129. doi:10.3389/fphar.2014.00129. eCollection 2014.
    141.    Calabrese V, Dattilo S, Petralia A, Parenti R, Pennisi M, Koverech G, Calabrese V, Graziano A, Monte I, Maiolino L, Ferreri T, Calabrese EJ. (2015) Analytical approaches to the diagnosis and treatment of aging and aging-related disease: redox status and proteomics. Free Radic Res. 49: 511-524.
    142.    Amadio M, Scapagnini G, Davinelli S, Calabrese V, Govoni S, Pascale A. (2015) Involvement of ELAV RNA-binding proteins in the post-transcriptional regulation of HO-1. Front Cell Neurosci. 8:459. doi: 10.3389/fncel.2014.00459.
    143.    Dattilo S, Mancuso C, Koverech G, Di Mauro P, Ontario ML, Petralia CC, Petralia A, Maiolino L, Serra A, Calabrese EJ, Calabrese V. (2015) Heat shock proteins and hormesis in the diagnosis and treatment of neurodegenerative diseases. Immun  Ageing. 12:20. doi: 10.1186/s12979-015-0046-8. eCollection 2015. 
    144.    Calabrese EJ, Dhawan G, Kapoor R, Iavicoli I, Calabrese V. (2015) What is hormesis and its relevance to healthy aging and longevity? Biogerontology 16:693-707.
    145.    Catino S, Paciello F, Miceli F, Rolesi R, Troiani D, Calabrese V, Santangelo R, Mancuso C. (2016) Ferulic Acid Regulates the Nrf2/Heme Oxygenase-1 System and Counteracts Trimethyltin-Induced Neuronal Damage in the Human Neuroblastoma Cell Line SH-SY5Y. Front Pharmacol. 8;6:305. doi: 10.3389/fphar.2015.00305.
    146.    Calabrese V., Davinelli S., Luca M., Zella D., Calabrese E.J.,  and Scapagnini G. (2015) Inflammaging, Oxidative Stress and Carnosine: Role of Hormetic Vitagenes. In: Imidazole Dipeptides : Chemistry, Analysis, Function and Effects.  Food and Nutritional Components in Focus. January(8), pp. 238-256. EPUB eISBN: 978-1-78262-655-8. DOI:10.1039/9781782622611-00238.
    147.    Trovato A, Siracusa R, Di Paola R, Scuto M, Fronte V, Koverech G, Luca M, Serra A, Toscano MA, Petralia A, Cuzzocrea S, Calabrese V. (2016) Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat  brain: Relevance to Alzheimer's disease pathogenesis. Neurotoxicology. 53:350-358.
    148.    Calabrese EJ, Dhawan G, Kapoor R, Iavicoli I, Calabrese V.  (2016) HORMESIS: A Fundamental Concept with Widespread Biological and Biomedical Applications. Gerontology. 62:530-535.
    149.    Pennisi M, Crupi R, Di Paola R, Ontario ML, Bella R, Calabrese EJ, Crea R, Cuzzocrea S, Calabrese V. (2016) Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease. J Neurosci Res. 2016 Nov 8. doi: 10.1002/jnr.23986.
    150.    Calabrese V, Giordano J, Signorile A, Laura Ontario M, Castorina S, De Pasquale C, Eckert G, Calabrese EJ. (2016)  Major pathogenic mechanisms in vascular dementia: Roles of cellular stress response and hormesis in neuroprotection. J Neurosci Res. 94:1588-1603.
    151.    Calabrese V, Giordano J, Ruggieri M, Berritta D, Trovato A, Ontario ML, Bianchini R, Calabrese EJ. (2016) Hormesis, cellular stress response, and redox homeostasis in autism spectrum disorders. J Neurosci Res. 2016 Dec;94(12):1488-1498. doi: 10.1002/jnr.23893.
    152.    Trovato A, Siracusa R, Di Paola R, Scuto M, Ontario ML, Bua O, Di Mauro P, Toscano MA, Petralia CC, Maiolino L, Serra A, Cuzzocrea S, Calabrese V. (2016) Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer's disease pathogenesis. Immun Ageing. 13:23. doi: 10.1186/s12979-016-0078-8. eCollection 2016.
    153.    Calabrese V., Crea R. (2016). Potential prevention and treatment of Neurodegenerative Diseases: Olive polyphenols and hydroxytyrosol. Eur. J. Neurodegenerative Diseases 5: 81-108.
    154.    Barros A.B., Bell V., Ferrão J., Calabrese V., Fernandes T.H. (2016). Mushroom Biomass: Some Clinical Implications of β-Glucans and Enzymes. Current Res. Nutrition and Food Science 4:  37-47.
    155.    Paterniti I, Campolo M, Siracusa R, Cordaro M, Di Paola R, Calabrese V, Navarra M, Cuzzocrea S, Esposito E. (2017) Liver X receptors activation, through TO901317 binding, reduces neuroinflammation in Parkinson's disease. PLoS One. 12(4):e0174470.
    156.    Calabrese V, Giordano J, Crupi R, Di Paola R, Ruggieri M, Bianchini R, Ontario ML, Cuzzocrea S, Calabrese EJ. (2017) Hormesis, cellular stress response and neuroinflammation in schizophrenia: Early onset versus late onset state. J Neurosci Res. 95:1182-1193.
    157.    Calabrese E.J., Calabrese V., Giordano J. (2017) The role of hormesis in the functional performance and protection of neural systems. Brain Circulation 3: 1-13.
    158.    Wang D., Calabrese E.J., Lian B., Lin Z., Calabrese V. (2017) Hormesis as a mechanistic approach to understanding herbal treatments in traditional Chinese medicine. Pharmacol Ther. Nov 8. pii: S0163-7258(17)30263-2. doi:10.1016/j.pharmthera.2017.10.013.
    159.    Miquel S, Champ C, Day J, Aarts E, Bahr BA, Bakker M, Bánáti D, Calabrese V, Cederholm T, Cryan J, Dye L, Farrimond JA, Korosi A, Layé S, Maudsley S, Milenkovic D, Mohajeri MH, Sijben J, Solomon A, Spencer JPE, Thuret S, Vanden Berghe W, Vauzour D, Vellas B, Wesnes K, Willatts P, Wittenberg R, Geurts L. (20017) Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions. Ageing Res Rev. 42:40-55.
    160.    Calabrese V, Santoro A, Monti D, Crupi R, Di Paola R, Latteri S, Cuzzocrea S, Zappia M, Giordano J, Calabrese EJ, Franceschi C.  (2017) Aging and Parkinson's Disease:  Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis. Free Radic Biol Med. 115: 80-91.
    161.    Peters V, Schmitt CP, Weigand T, Klingbeil K, Thiel C, van den Berg A, Calabrese V, Nawroth P, Fleming T, Forsberg E, Wagner AH, Hecker M, Vistoli G. (2017) Allosteric inhibition of carnosinase (CN1) by inducing a conformational shift. J  Enzyme Inhib Med Chem. 32(1):1102-1110.
    162.    Trovato Salinaro A, Pennisi M, Di Paola R, Scuto M, Crupi R, Cambria MT, Ontario ML, Tomasello M, Uva M, Maiolino L, Calabrese EJ, Cuzzocrea S, Calabrese V. (2018) Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer's disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms. Immun Ageing. 2018 Feb 14;15:8. doi: 10.1186/s12979-017-0108-1.
    163.    Calabrese EJ, Iavicoli I, Calabrese V, Cory-Slechta DA, Giordano J. (2018) Elemental mercury neurotoxicity and clinical recovery of function: A review of findings, and implications for occupational health. Environ Res. 9;163:134-148. doi: 10.1016/j.envres.2018.01.021.

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    Editorial Board

    Alberto Deganello
    Assistant Professor
    Department of Otolaryngologist / Head and Neck Surgeon
    University of Florence
    Italy
    adeganello@hotmail.com
    AOR

    Research Interest: Head and neck oncology,and head and neck reconstructive surgery

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    Sabrina Danniela
    Department of Otolaryngology
    Mcgill University
    Canada
    sabrina.wurzba@gmail.com
    AOR

    Research Interest: McGill Head and Neck Oncology.


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    Suzanne S Abraham
    Assistant Professor
    Department of Surgery (Otolaryngology)
    Australia
    SUABRAHAM@aol.com
    AOR

    Research Interest:  head neck cancer as well as dysphagia to my areas of expertise.


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    ZaglskiOlaf
    Professor
    Department of Otolaryngology
    Jagiellonian University
    Poland
    olafzag@gmail.com
    AOR

    Research Interest: Paediatric otorhinolaryngology, balance, larynx, voice.

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    Katia Nemr
    Professor
    Department of Physiotherapy
    University of Sao Paulo
    Brazil
    knemr@usp.br
    AOR

    Research Interest: Voice, Voice disorders, rehabilitation os head and neck surgery.

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    Zhengcai Lou
    Professor
    Department of Otorhinolaryngology
    Wenzhou Medical University
    China
    louzhengcai@163.com
    AOR

    Research Interest: Tympanic membrane regeneration, and  laryngopharyngeal reflux

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    Katsumi Doi
    Professor
    Department of Otolaryngology
    Kinki University
    Japan
    kdoi@med.kindai.ac.jp
    AOR

    Research Interest: Otology”, “neuro-otology”,“audiology”, “middle ear surgery”, and “inner ear.


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    Xiangning Zhang
    Associate Professor
    Department of Pathophysiology
    Guangdong Medical College
    China
    zhangxn_2006@126.com
    AOR

    Research Interest: Nasopharyngeal carcinoma (NPC); Tumor suppressor genes; cell cycle; cyclins; signal transduction; mitogen activated protein kinase(MAPK); apoptosis; death receptor; caspases; mitochondrion; tumorigenic viruses; Epstein-Barr virus (EBV).

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    Abdel Razek
    Diagnostic Radiology Department
    Mansoura University
    Egypt
    arazek@mans.edu.eg
    AOR
    More Info.
    Qian-Hui Qiu
    Department of Otorhinolaryngology
    Guangzhou University
    PR China
    qiuqianhui@hotmail.com
    AOR
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    Pei-Jian Peng
    Associate Professor
    Department of Medical Oncology
    Sun-Yat-Sen University
    China
    pengpjian@163.com
    AOR

    Research Interest: Tumor chemotherapy and pharmacology, especially in the diagnosis and treatment of Nasopharyngeal Carcinoma, lung cancer, breast cancer, and gastrointestinal malignant tumors.

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    Anna Karolina Starzyńska
    Professor
    Department of Oral Surgery
    Medical University of Gdańsk
    Poland
    ast@gumed.edu.pl
    AOR

    In 1993 I was employed as an assistant in the Public Health and Social Medicine Department of Medical University of Gdańsk.

    Then I undertook research concerning Polish society health status, health promotion, health care service activity and the health policy. These areas of interest were connected with the profile of my place of work.

    In years 1995-2017 I worked as a research-and-teaching assistant, later as a senior lecturer and an assistant professor consequently, in the Department of Maxillofacial and Oral Surgery of Medical University of Gdańsk. At the time, I commenced my research on head and neck neoplasms, as well as trauma and inflammation processes of head and neck region. Since 12th of April 2017 I had been acting Head of Oral Surgery Department of Medical University of Gdańsk and since 1st of June 2018 I have been Head of Oral Surgery Department of Medical University of Gdańsk. On 1st of January 2018 I was hired as an associate professor in Medical University of Gdańsk. On the 28th of November 2019 I was hired as a professor at the Medical University of Gdańsk.

    Research Interest: Oncology, laryngology, oral surgery

    Grants: 6

    Number of publications: 175

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    Maria J. Worsham
    Senior Scientist
    Department of Otolaryngology Head and Neck Surgery
    Henry Ford Hospital
    USA
    mworsha1@hfhs.org
    AOR

    Research Interest: Strategic Global Mining of Methylated Promoter Sites in a Diverse ER-Negative Primary Care Breast Cancer Population.


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    Itzhak Braverman
    Assistant Professor
    Department of Otolaryngology, Head and Neck Surgery
    Hillel Yaffe Medical Center
    Israel
    braverman@hy.health.gov.il
    AOR

    Research Interest: Rhinology, nose and paranasal sinuses physiology and diseases (human ciliary function in normal and chronic sinusitis), balloon sinuplasty technology, snoring and sleep apnea, diagnosis and treatment of obstructing sleep apnea, chronic tonsillitis, coblation technology, dysphagia.

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    James Paul Dworkin-Valenti
    Professor
    Otolaryngology
    Michigan State University
    USA
    voicedx@yahoo.com
    AOR

    Dr. Dworkin-Valenti received his Ph.D. from the University of Buffalo with special focus on speech and voice physiology. He completed a post-doctoral fellowship at the Mayo Clinic, concentrating his research on amyotrophic lateral sclerosis in the Department of Neurology. He is currently Director of Clinical Research at the Detroit Medical Center, in cooperation with the Department of Otolaryngology ENT Residency Program. Throughout his career, Dr. Dworkin-Valenti has cumulatively published more than 125 scientific journal articles, textbooks, and book chapters on various subjects, including vocal pathologies, otolaryngic allergy, and motor speech and developmental communication disorders.

    Grants: 

    1.    Dworkin, J.P. Protrusive lingual force and lingual diadochokinetic rates: A comparative analysis between normal and lisping speakers. Journal of Language, Speech & Hearing in Schools, 9:8-16, 1978.

    2.   Dworkin, J.P. A therapeutic technique for the improvement of lingua-alveolar valving abilities. Journal of Language, Speech & Hearing in Schools, 9:162-175, 1978.    

    3.    Dworkin, J.P. A review of motor speech disorders (Part I). Journal of National Student Speech & Hearing Assoc., December, 12-36, 1978. 

    4.    Dworkin, J.P. Differential diagnosis of motor speech disorders: The clinical examination of the speech mechanism (Part II). Journal of National Student Speech & Hearing Assoc., December,37-62, 1978.

    5.    Dworkin, J.P. The influence of lingual muscular strength on articulatory proficiency. Clinical Otolaryngology & Allied Sciences, 4:413-420, 1979.

    6.   Dworkin, J.P. & Hartman, D.E. Progressive speech deterioration and dysphagia in ALS.                     Archives of Physical Medicine & Rehabilitation, 60: 423-425, 1979.

    7.   Abkarian, G.G., Dworkin, J.P., & Brown, S. Signed English as a transition step in the treatment         of a child with Reye’s syndrome. Human Communication, Spring, 375-380, 1980.

    8.   Dworkin, J.P. Characteristics of frontal lispers clustered according to severity. Journal of Speech       & Hearing Disorders, 45:37-44, 1980.

    9.   Dworkin, J.P., Aronson, A.E. & Mulder, D.W. Tongue force in normals and dysarthric patients          with amyotrophic lateral sclerosis. Journal of Speech & Hearing Research, 23:828-837, 1980.

    10.  Dworkin, J.P., Hartman D.E. & Keith, R.L. Tongue strength following total laryngectomy (Part         I). Laryngoscope, 90:680-684, 1980.

    11.  Dworkin, J.P., & Hartman, D.E. Tongue strength in artificial alaryngeal speech (Part II).

           Laryngoscope, 90:867-870, 1980.

    12.  Dworkin, J.P. & Culatta, R.A. Tongue strength: Its relationship to tongue thrusting, open bite            and articulatory proficiency. Journal of Speech & Hearing Disorders, 45:277-282, 1980.

    13.  Dworkin, J.P. & Johns, D.F. Management of Velopharyngeal incompetence in dysarthria: A               historical review. Clinical Otolaryngology & Allied Sciences, 5:61-74, 1980.

    14.  Dworkin, J.P. & Sparker, A. Surgical vocal rehabilitation following total laryngectomy: a state          of the art report. Clinical Otolaryngology & Allied Sciences, 5: 339-351, 1980.

    15.   Dworkin, J.P. Tongue strength measurement in patients with ALS: Qualitative vs. quantitative           procedures. Archives of Physical Medicine & Rehabilitation, 61: 422-424, 1980.

    16.   Monahan, D. & Dworkin, J.P. A brief review of vocal nodules. Kentucky Journal of Speech-             Language Pathology & Audiology, 4: 20-24, 1980.

    17.   Dworkin, J.P. Book review. Clinical Otolaryngology & Allied Sciences, 1981.

    18.   Dworkin, J.P. Book review. Clinical Otolaryngology & Allied Sciences, 1982.

    19.   Hartman, D.E. & Dworkin J.P. Ratings of manual activity for two forms of alaryngeal speech.           Australian Journal of Human Communication, 10:31-36, 1982.

    20.   Dworkin, J.P. Glossectomy: a case report. Archives of Physical Medicine & Rehabilitation, 63:        182-183, 1982.

    21.   Dworkin, J.P. & Banton, A. Esophageal vs. artificial instrument speech rehabilitation methods           for the laryngectomee. Clinical Otolaryngology & Allied Sciences, 7: 269-277, 1982.

    23.   Dworkin, J.P. Book review. Clinical Otolaryngology & Allied Sciences, 1983.

    24.   Dworkin, J.P. Book review. Clinical Otolaryngology & Allied Sciences, 1984.

    25.   Dworkin, J.P. Dysphagia. Journal of Childhood Communication Disorders, 7: 48-54, 1985.

    26.   Dworkin, J.P. & Culatta, R.A. Oral structural and neuromuscular characteristics in children with         normal and disordered articulation. Journal of Speech & Hearing Disorders, 50:150-156, 1985.

    27.   Dworkin, J.P. & Aronson, A.E. Tongue Strength and Alternate Motion Rates in Normal and              Dysarthric Subjects. Journal of Communication Disorders, 1986

    28.   Dworkin, J.P., Abkarian G.G. & Johns, D.F. Apraxia of Speech: A Therapeutic Regimen.                  Journal of Speech & Hearing Disorders, 53:280-294, 1988.

    29.   Dworkin, J.P. & Culatta, R.A. Some comments about oropharyngeal motor development in                children. Journal of Speech & Hearing Disorders, 53: 483-485, 1988.

    30.   Dworkin, J.P. & Petrucci-Coley, T. Closed head injury:A look from the speech physiology lab.          Texas Journal of Audiology & Speech Pathology, 14: 8-13, 1988.

    31.   Dworkin, J.P. & Nadal, J.C. Nonsurgical treatment of drooling in a patient with closed head               injury and severe dysarthria. Dysphagia, 6:40-49, 1991.

    32.   Hartman, D. & Dworkin, J.P. Motor speech disorders. Gundersen Clinic Journal of Medicine,            May, 1993.

    33.    Abkarian, G.G. & Dworkin, J.P. Treatment of Severe Motor Speech Disorders. Give speech a            chance. Journal of Medical Speech-Language Pathology, 1:285-287, 1993.       

    34.    Purser, S., Meleca, R., Dworkin, J.P. & Stachler, R. The action of the cricoarytenoid joint: A             reappraisal. Otolaryngology, Head & Neck Surgery, 113, 169-170, 1995.

    35.   Dworkin, J.P. & Arden R.L.  Phonosurgical Management of Laryngeal Lupus. Journal of                   Medical Speech-Language Pathology, 3, 201-215, 1995.

    36.   Dworkin, J.P. Bite Block Therapy for oromandibular Dystonia.  Journal of Medical Speech-               Language Pathology,  4:47-56, 1996.

    37.   Dworkin, J.P. & Abkarian, G. Treatment of phonation in a patient with dysarthria secondary to          severe closed head injury. Journal of Medical Speech -Language Pathology, 4:105-116, 1996.

    38.   Dworkin, J.P. & Aref, A. Voice laboratory measures following RT for T1N0 glottic CA.                    Journal of Medical Speech-Language Pathology, 5:61-73, 1997.

    39.   Aref, A., Dworkin, J., Devi, S. Denton, L., & Fontanesi, J. Objective evaluation of the quality of         voice following RT for T1 glottic CA. Radiotherapy & Oncology, 45:149-153, 1997.

    40.   Danish, M. Dworkin, J.P., & Meleca, R. Airway obstruction, saccular cysts: A review of the             disease entity and treatment approach emphasizing complete endoscopic CO2 laser excision.             Archives of Otolaryngology, 124: 593-596, 1998.

    41.   Dworkin, J., Meleca, R., Simpson, M., Zormeier, M., Garfield, I., Jacobs,J., & Mathog, R. Pharyngoesophageal segment vibratory characteristics in total laryngectomeeds who use the tracheoesophageal method of speech production.Laryngoscope, 108, 12: 1773-81, 1998.

    42.   Arden, R., Dworkin, J., & Garfield, I. Marlex mesh suspension of the floor of mouth in the glossectomee.  Operative techniques in Otolaryngology-Head and Neck Surgery, 9, 3:119- 122, 1998.

    43.  Dworkin, J., Meleca, R., Simpson, M., Zormeier, M., Garfield, I., Jacobs, Mathog, R. Vibratory         characteristics of the PE segment in total laryngectomees. Journal of Medical Speech-Language         Pathology, 7: 1-18, 1999.

    44.  Dworkin, J., Meleca, R., Abkarian, G. et al.  Phonation subsystem of laryngectomees following RT for T1 glottic carcinoma:  A prospective voice  laboratory investigation. Journal of Medical Speech-Language Pathology, 7: 181-194, 1999.

    45.  Zormeier, M., Meleca, R., Dworkin, J., & Simpson, M., Botox injection to improve TE speech after total laryngectomy. Otolaryngology, Head & Neck Surgery, 120: 314-319, 1999.

    46.    Dworkin, J.P. & Meleca, R. Behavioral therapy for organic voice tremor. Phonoscope, 2: 113-          122, 1999.

    47.   Dworkin, J.P., Rachel, J., & Meleca, R. Evaluation of postsurgical vocal fold paralysis.                      Phonoscope, 2: 193-202, 1999.

    48.   Dworkin, J.P. & Meleca, R. Muscle tension dysphonia. Current Opinion in Otolaryngology, 8:          169-173, 2000.

    49.   Dworkin, J.P., Meleca, R., & Garfield, I., Use of topical Lidocaine in the treatment of muscle            tension dysphonia. Journal of Voice, 14: 567-575, 2000.

    50.   Ahsan, S., Dworkin, J.P. & Meleca, R. Botox of the cricopharyngeal muscle for treatment of             dysphagia. Otolaryngology Head & Neck Surgery, 112: 691-695, 2000.

    51.   Meleca, R., Dworkin, J., Zormeier, M., Simpson, M, et al. Videosroboscopy of the P-E Segment         in laryngectomees treated with Botox. Otolaryngology Head & Neck Surgery, 123: 38-43, 2000.

    52.   Zacharek, M., Pasha, R., Meleca, R., Dworkin, J., et al. Functional outcomes after supracricoid          laryngectomy. Laryngoscope, 111: 1558-1564, 2001.

    53.   Dworkin, J.P., Meleca, R., & Culatta, R. Laryngeal manifestations of speech dysfluency:                    Topical anesthesia treatment approach. Laryngoscope, 112: 936-937, 2002.

    54.   Dworkin, J.P., Meleca, R., Oh, C., & Simpson, M. Use of esophageal videoendoscopy for the            differential diagnosis and treatment of poor TE speech. Journal of Medical Speech Language             Pathology, 10: 133-142, 2002.

    55.   Dworkin, J.P., Culatta, R., Abkarian, G., & Meleca, R. Laryngeal anesthetization for the                     treatment of acquired disfluency: A case study. Journal of Fluency Disorders, 27: 215-226,                 2002.

    56.   Leonard, R., Dworkin, J.P., Meleca, R., Colton, R., et al. Assessment of the disordered voice.            Journal of Medical Speech language Pathology, 10: 111-131, 2002.

    57.   Oh, C., Meleca, R., Simpson, M. & Dworkin, J. Fiberoptic examinatin of the P-E segment in             tracheoesophageal speakers. Archives of Otolaryngology, Head & Neck Surgery, 128: 692-697,         2002.

    58.   Meleca, R., Dworkin, J., Kewson, D., Stachler, R, & Hill, S. Functional outcomes following             non-surgical treatment for advanced stage laryngeal carcinoma. Laryngoscope , 113, 720-728,            2003.

    59.   Dworkin, J.P., Meleca, R. & Stachler, R. More on the role of the mandible in speech                          production: Clinical correlates of Green, Moore and Reilly’s findings. Journal of Speech,                   Language & Hearing Research , 46, 1016-1020 (2003).

    60.   Abkarian, G., Dworkin, J.P. & Abkarian, A. Fathers’ speech to their children: Perfect pitch or             tin ear? Fathering, 1: 27-50, 2003.

    61.   Reidy, P., Dworkin, J.P., & Krouse, J. Laryngeal effects of antigen stimulation challenge with            perennial allergen D. Pteronyssinus. Otolaryngology-Head & Neck Surgery, 128, 455-462                  (2003).

    62.   Dworkin, J.P., Meleca, R., Zacharek, M., Stachler, R., Pasha, R. et al. Voice and deglutition               functioning following the supracricoid laryngectomy and total laryngectomy procedures for                advanced stage laryngeal carcinoma. Otolaryngology Head & Neck Surgery, 129, 311-320                 (2003).

    63.   Karpenko, A., Dworkin, J.P., Meleca, R. & Stachler, R. Cymetra injection for unilateral vocal            fold paralysis. Annals Otology Rhinology Laryngology, 112, 927-934 (2003).

    64.   Dworkin, J.P., Abkarian, G., Stachler, R., Culatta, R. & Meleca, R. Is voice amplification for             teachers with dysphonia really beneficial?  Journal Speech, Language, & Hearing Research, 47,         353-357 (2004).

    65.   Dworkin, J.P., Marunick, M.T., & Krouse, J.H. Velopharyngeal dysfunction: speech                           characteristics, variable etiologies, evaluation techniques, and differential treatments. Language,         Speech, and Hearing Services in Schools, 35, 333-353 (2004).

    66.   Dworkin, J.P., Marunick, M.T., & Stachler, R.  Neurogenic velopharyngeal incompetence:                 Multidisciplinary diagnosis and treatment. Journal of Applied Research in Clinical Dentistry, 1,         35-46 (2004).

    67.   Dworkin, J.P., Stachler, R.J., Kewson, D., Meleca, R.J., & Garfield, I. Videostroboscopy,                   mirror, and fiberoptic laryngoscopy: Objective comparisons. Journal of Medical Speech-                    Language Pathology, 12, 99-106 (2004).

    68.   Dworkin, J. Apraxia of speech. The Gale Encyclopedia of Neurological Disorders, 2004.

    69.   Dworkin, J. The dysarthrias. The Gale Encyclopedia of Neurological Disorders. 2004.

    70.   Dworkin, J.P., Hill, S., Stachler, R.J., & Kewson, D. Swallowing function outcomes following          nonsurgical therapy for advanced stage laryngeal carcinoma. Dysphagia , 10, 66-74 (2006).


    71.   Dworkin, J.P., Stachler, R.J., Shaw, A., & Meleca, R.J. Medialization thyroplasty versus                    injection laryngoplasty for unilateral vocal fold paralysis: A comparative analysis of functional          outcomes. Journal of Medical Speech-Language pathology,  14, 1-13 (2006).

    72.   Dworkin, J.P., Dickson, M., Stachler, R. & Yoo, G. Tracheoesophageal speech rehabilitation:           Managing complications to ensure successful treatment outcomes. Journal of Medical Speech-           language Pathology,  14, 97-109 (2006).

    73.   Dworkin, J.P. Laryngeal inflammation: Types, causes, & treatments. Otolaryngologic Clinics of         North America, 419-436 (2008).

    74.   Krouse, J., Dworkin, J., Carron, M., &  Stachler, R. Baseline laryngeal effects among                         individuals with dust mite allergy. Otolaryngology Head & Neck Surgery, 149-151 (2008).

    75.   Dworkin, J.P., Reidy, P., Krouse, J.H. & Stachler, R.J. Effects of sequential dust mite                         stimulation: on the anatomy and physiology of the larynx. ENT Journal, 88, 793-799 (2009).

    76.   Dworkin, J.P. & Treadway, C. Idiopathic vocal fold paralysis: Treatments and outcomes.                   Journal of Neurological Sciences , 284, 56-62 (2009).

    77.   Mao, J., Kayali, F., Dworkin, J., Stachler, R., & Mathog, R. Conservative management of                  iatrogenic esophageal perforation in head and neck cancer patients with esophageal                             stricture. Otolaryngology-Head & Neck Surgery, 505-511 (2009).

    78.   Dworkin, J.P., Klapchar, R., & Madgy, D. Masses that arise within or encroach upon the                    parapharyngeal space. Journal of Medical Speech-Language Pathology , 19, 31-44 (2011).

    79.   Dyer, S., Sirigiri, R., Saraiya, S., Dworkin, JP., et al. Congenital lobular capillary hemangioma of the larynx. International Journal of Pediatric Otolaryngology,  (2011).

    80.   Humphreys, I, Saraiya, S., Belenky, W, & Dworkin, J.  Nasal Packing with Strips of Cured                Pork as Treatment for Uncontrollable Epistaxis in a Patient with                                                           GlanzmannThrombasthenia.  Annals of Otology, Rhinology, & Laryngology, 120 (11),  732- 736, (2011).

    81.   Thottam,P.J., Haupert,M., Saraiya, S., Dworkin,J.P.,  Sirigiri,R., & Belenky, W. Functional              endoscopic sinus surgery  (FESS) alone versus balloon catheter sinuplasty (BCS) and                         ethmoidectomy: A comparative outcome analysis in pediatric chronic rhinosinusitis,  Int. J.                Pediatic Otorhinolaryngol,  76 (9),1355-60 (2012).

    82.  Dworkin, J.  Dysarthria.The Gale Encyclopedia of Neurological Disorders, Second Edition. Ed.Brigham Narins, Gale, (2012).

    83.   Meshkinfam, S., Haupert, M., Poulik, J., Dworkin, J., Tabassum, F., Zegarra-Linares, R.McGrath, E. Mycobacterium Avium Complex Associated Bronchocentric Granulomatosis of the Mainstem Bronchus in an Immunocompetent Child Presenting as an Airway Foreign Body. Consultant in Primary Care, 108-110, February, (2013).

    84.   Dyer, S., Durvasula,P., Bathula,S., Sana,S., Madgy,D., Haupert,M., & Dworkin,J.                               Intraoperative Use of FloSeal to  Prevent Adverse Postoperative Outcomes in pediatric                       patients. Otolaryngology-Head and Neck Surgery, 149, 312-317 (2013).  

    85.   Rutt, A., Dworkin,J., & Stern, N.  Supraglottic Obstruction in an adult with inspiratory arytenoid cartilage prolapse. Otolaryngology (open access) 4: 165 (2014).

    86.  Dworkin, J.P., Thottam,P.J., Madgy, D., & Saraiya, S.  Pathologies that Threaten the                          Pediatric Airway. Journal of Medical Speech-Language Pathology, 21 (2), 91-106, (2014).  

    87.  Cannito, M., Chorna, L., Kahane, J, & Dworkin, J.  Influence of voicing characteristics on                 sentence productions in abductor versus adductor spasmodic dysphonia. Journal of Voice, 28             (3), 394-407 (2014).        

    88.   Rutt, A., Dworkin J., Kim H, et al.  Swallowing function after non-surgical treatment for                   advanced hypopharyngeal or laryngeal cancer.  Journal of Medical Speech-Language                          pathology, 21 (4), 357-368 (2014).

    89.   P.J. Thottam, C. Metz,  M.C. Kieu, J. Dworkin-Valenti, J. Jagini. FESS versus Balloon                      Sinuplasty as  Long-term Treatment for Pediatric Chronic Rhinosinusitis: A 2-Year Post-                   operative Analysis.  Indian Journal of Otolaryngology and Head and Neck Surgery, January,              (2015).        

    90.   Dworkin-Valenti, J., Dowdall, J.,  Kubik, M, Thottam, P., & Folbe, A.  Role of the modified              barium swallow study and esophagram in patients with chief complaints of a globus sensation.           Dysphagia,  DOI 10.1007/s00455-015-9629-y,  (2015).   

    91.   Belafsky, P, Peake, J, Smiley-Jewell, S, Verma, S, Dworkin-Valenti, J., & Pinkerton, K.                     Eosinophilic laryngitis. Laryngoscope, November, DOI:10.1002/lary.25467, (2015).

    92.   Sugihara, E., Dworkin-Valenti, J., Thottam, P., & Taweel, J. Numb Chin Syndrome and                     Metastatic Lung Adenocarcinoma: A Prolonged Outcome and Propensity for Younger Age.                Jacobs Journal of Otolaryngology, 1(2): 010, (2015).

    93.   Dworkin-Valenti, J , Vandjelovic, N. & Bathula,S. The therapeutic value of trans-cricothyroid           injections for  intractable conversion reaction mutism. Annals of Rhinology, Laryngology,                 Otology, 2(8): 1055, (2015).

    94.   Dworkin-Valenti, J. Sugihara, E., Stern, N., et al.  Laryngeal inflammation.  Annals of                        Rhinology, Laryngology, Otology, 2(9): 1058, (2015).

    95.  Klapchar, R., Crigger, B., & Dworkin-Valenti, J. Proliferating trichilemmal cyst with                         lymphadenopathy:  A discussion of cutaneous neoplasms involving the scalp. Journal of Ear,

           Nose, and Throat Disorders, 1 (1) 1002, 1-4 (2016).

    96.   Lane, J., Dworkin-Valenti, J., & Haupert, M. Postoperative Tonsillectomy Bleeding                            Complications in Children: A Comparison of Three Surgical Techniques. International Journal          of Pediatric Otolaryngology, 88, 184-188 (2016).

    97.    Kelley, B., Vandjelovic, N., Neil, D., Amjad, E. & Dworkin-Valenti, J. Tumoral calcinosis involving the airway. Journal of Ear, Nose, and Throat Disorders, 1 (1):1101-1104 (2016).

    98.    Dworkin-Valenti, J., McNulty, B., Amjad, E., Sugihara, E., and Naumann, I. Otogenic versus neurogenic dizziness: The neurotology perspective. Current Trends in Neurology, 10, 1-12 (2016).

    99.    Stachler, R. & Dworkin-Valenti, J. Allergic Laryngitis: Unraveling the Myths.

    Current Opinion in Otolaryngology and Head & Neck Surgery,  25, 242-246 (2017).

    100.    Patel, S., Dworkin-Valenti, J., & Haupert, M. Secondary airway lesions in patients with                      laryngomalacia. Otolaryngology, Head & Neck Surgery. In Submission.

    101.    Szekely, J., Amjad, E., Evans, M., & Dworkin-Valenti, J. Plummer Vinson Syndrome: Fatal progression in an African American female. Annals of Otolaryngology and Rhinology, 4:1192-1194 (2017).

    102.    Dworkin-Valenti, J., Stachler, R., Stern, N., & Amjad, E. Pathophysiologic perspectives on muscle tension dysphonia. Annals of Otolaryngology and Rhinology. In Submission.
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    Impact of perceptual-learning strategies and background noise on disordered speech intelligibility

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    Author(s): Kaitlyn Kuntzman*, Wellington Davis III, and Debra Esernio-Jenssen*

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    Second localization of a lymphoma affecting the nasopharynx

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    Awareness of smell exercise after smell dysfunction related to COVID-19 in Alahsaa, Saudi Arabia

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    Published On: September 21, 2022 | Pages: 014 - 019

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    Effect of smoking on status of hearing: A cross-sectional study

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    Published On: July 29, 2022 | Pages: 009 - 013

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    Remarks on the theory of hearing-a traveling wave part two

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    Published On: January 04, 2022 | Pages: 001 - 006

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    Editor-in-Chief

    Malgorzata Gabriela WASNIEWSKA
    University of Messina, Italy
    International Journal of Clinical Endocrinology and Metabolism
    Prof. Pierre Guertin
    Laval University, Canada
    International Journal of Pharmaceutical Sciences and Developmental Research
    Jiexiong Feng
    Huazong University of Science and Technology, China
    Open Journal of Pediatrics and Child Health
    Erich Cosmi
    University of Padua, Italy
    Journal of Gynecological Research and Obstetrics
    William CS Cho
    Queen Elizabeth Hospital, Hong Kong
    International Journal of Immunotherapy and Cancer Research
    Massimiliano VISOCCHI 
    Catholic University of Rome, Italy
    Open Journal of Orthopedics and Rheumatology
    Hongxing Dai
    Beijing University of Technology , PR China
    Journal of Civil Engineering and Environmental Sciences
    Peter J Catalano
    Tufts University, USA
    Archives of Otolaryngology and Rhinology
    M.Waheed Roomi
    Dr. Rath Research Institute
    1260 Memorex Drive, Santa Clara, USA
    Global Journal of Cancer Therapy
    Osmar Antonio Centurion
    Asuncion National University, Paraguay
    Global Journal of Medical and Clinical Case Reports

    NIH Funded Articles

    How Anterior Cruciate Ligament Injury was averted during Knee Collapse in a NBA Point Guard Significance of Cancer Stem Cells in Anti-Cancer Therapies Endothelial Progenitor Cells in Breast Cancer Variation among gari samples of some yellow cassava (Manihot esculenta Crantz) varieties for change in color during storage Validity of Ratings of Perceived Exertion in Patients with Type 2 Diabetes Diabetic Retinopathy: Focus on Minority Populations Neural Response During a Mechanically Assisted Spinal Manipulation in an Animal Model: A Pilot Study Hepatitis B Vaccination Rate in Patients with Diabetes: Assessment of Racial and Socioeconomic Disparity Ethnic Differences in Abstinence Self-Efficacy among Recovering Individuals Buprenorphine Maintenance for Opioid Dependence in Public Sector Healthcare: Benefits and Barriers

    Research Articles

    Dualistic relativity: Unification of Einstein’s Special Relativity and de Broglie’s Matter–Wave Theory
    June 18, 2022    The Effects of Maxillary Protrusion on Pharyngeal Airway Dimensions
    September 08, 2014    Evaluation the Viability of the Saccharomyces Boulardii Bld-3 and its Influence on the Colonic Microbiota Composition by SHIME
    August 20, 2018

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